2JJ8

Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase

Summary for 2JJ8

Related1ZM7 2VPP 2VP5 1ZMX 2VP4 1J90 2VP0 2JCS 1OT3 2VP6 1OE0 2VP2 2VP9 2VQS
DescriptorDEOXYNUCLEOSIDE KINASE, SULFATE ION, 3'-azido-3'-deoxythymidine, ... (4 entities in total)
Functional Keywordsatp-binding, dna synthesis, phosphoprotein, feedback inhibition, salvage pathway, nucleotide-binding, dttp, transferase
Biological sourceDROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains4
Total molecular weight109464.3
Authors
Mikkelsen, N.E.,Munch-Petersen, B.,Eklund, H. (deposition date: 2008-03-19, release date: 2008-04-29, Last modification date: 2012-07-25)
Primary citation
Mikkelsen, N.E.,Munch-Petersen, B.,Eklund, H.
Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275:2151-, 2008
PubMed: 18384378 (PDB entries with the same primary citation)
DOI: 10.1111/J.1742-4658.2008.06369.X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26730.7%3.3%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report