2JCS

Active site mutant of dNK from D. melanogaster with dTTP bound

Summary for 2JCS

Related1J90 1OE0 1OT3 1ZM7 1ZMX
DescriptorDEOXYNUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordskinase, transferase, atp-binding, dna synthesis, nucleotide- binding, deoxyribonucleoside kinase
Biological sourceDROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains2
Total molecular weight54798.31
Authors
Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B. (deposition date: 2007-01-03, release date: 2007-02-27, Last modification date: 2018-01-17)
Primary citation
Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B.
Functional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity.
FEBS J., 274:1542-, 2007
PubMed: 17302737 (PDB entries with the same primary citation)
DOI: 10.1111/J.1742-4658.2007.05701.X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers20.3%8.5%9.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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