2JCS

Active site mutant of dNK from D. melanogaster with dTTP bound

Summary for 2JCS

Entry DOI	10.2210/pdb2jcs/pdb
Related	1J90 1OE0 1OT3 1ZM7 1ZMX
Descriptor	DEOXYNUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	kinase, transferase, atp-binding, dna synthesis, nucleotide- binding, deoxyribonucleoside kinase
Biological source	DROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains	2
Total formula weight	54798.31
Authors	Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B. (deposition date: 2007-01-03, release date: 2007-02-27, Last modification date: 2023-12-13)
Primary citation	Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B. Functional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity. FEBS J., 274:1542-, 2007 Cited by PubMed: 17302737 DOI: 10.1111/J.1742-4658.2007.05701.X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation