2JCS
Active site mutant of dNK from D. melanogaster with dTTP bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DEOXYNUCLEOSIDE KINASE | polymer | 230 | 26892.7 | 2 | UniProt (Q9XZT6) Pfam (PF01712) | DROSOPHILA MELANOGASTER (FRUIT FLY) | DEOXYRIBONUCLEOSIDE KINASE, DM-DNK, MULTISPECIFIC DEOXYNUCLEOSIDE KINASE |
| 2 | C, E (A, B) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 2 | Chemie (TTP) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 230 (UniProt: Q9XZT6)
| PDB | External Database | Details |
|---|---|---|
| Asp 52 | Glu 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53785.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1012.9 | |
| All* | Total formula weight | 54798.3 |
