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1QME
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PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor:PENICILLIN-BINDING PROTEIN 2X, SULFATE ION
Authors:Gordon, E.J., Mouz, N., Duee, E., Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
1QMF
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PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX
Descriptor:PENICILLIN-BINDING PROTEIN 2X, 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM)
Authors:Gordon, E.J., Mouz, N., Duee, E., Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
J.Mol.Biol., 299, 2000
1K25
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PBP2X FROM A HIGHLY PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE CLINICAL ISOLATE
Descriptor:low-affinity PENICILLIN-BINDING PROTEIN 2X
Authors:Dessen, A., Mouz, N., Hopkins, J., Dideberg, O.
Deposit date:2001-09-26
Release date:2001-10-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
J.Biol.Chem., 276, 2001
1PMD
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PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor:PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME
Authors:Pares, S., Mouz, N., Dideberg, O.
Deposit date:1996-02-05
Release date:1997-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
Nat.Struct.Biol., 3, 1996
2X7P
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THE CONSERVED CANDIDA ALBICANS CA3427 GENE PRODUCT DEFINES A NEW FAMILY OF PROTEINS EXHIBITING THE GENERIC PERIPLASMIC BINDING PROTEIN STRUCTURAL FOLD
Descriptor:POSSIBLE THIAMINE BIOSYNTHESIS ENZYME, CALCIUM ION, CHLORIDE ION, ...
Authors:Santini, S., Monchois, V., Mouz, N., Rousselle, T., Claverie, J.M., Abergel, C.
Deposit date:2010-03-03
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:The Conserved Candida Albicans Ca3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold
Plos One, 6, 2011
2X7Q
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THE CONSERVED CANDIDA ALBICANS CA3427 GENE PRODUCT DEFINES A NEW FAMILY OF PROTEINS EXHIBITING THE GENERIC PERIPLASMIC BINDING PROTEIN STRUCTURAL FOLD
Descriptor:POSSIBLE THIAMINE BIOSYNTHESIS ENZYME, GLYCEROL, CALCIUM ION
Authors:Santini, S., Monchois, V., Mouz, N., Rousselle, T., Claverie, J.M., Abergel, C.
Deposit date:2010-03-03
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Conserved Candida Albicans Ca3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold
Plos One, 6, 2011
1PYY
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DOUBLE MUTANT PBP2X T338A/M339F FROM STREPTOCOCCUS PNEUMONIAE STRAIN R6 AT 2.4 A RESOLUTION
Descriptor:Penicillin-binding protein 2X, SULFATE ION, N-OCTANOYLSUCROSE, ...
Authors:Chesnel, L., Pernot, L., Lemaire, D., Champelovier, D., Croize, J., Dideberg, O., Vernet, T., Zapun, A.
Deposit date:2003-07-09
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains
J.Biol.Chem., 278, 2003
1RP5
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PBP2X FROM STREPTOCOCCUS PNEUMONIAE STRAIN 5259 WITH REDUCED SUSCEPTIBILITY TO BETA-LACTAM ANTIBIOTICS
Descriptor:penicillin-binding protein 2x, SULFATE ION
Authors:Pernot, L., Chesnel, L., Legouellec, A., Croize, J., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2003-12-03
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
J.Biol.Chem., 279, 2004
2G9Z
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THIAMIN PYROPHOSPHOKINASE FROM CANDIDA ALBICANS
Descriptor:thiamine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Abergel, C., Santini, S., Monchois, V., Rousselle, T., Claverie, J.M., Bacterial targets at IGS-CNRS, France (BIGS)
Deposit date:2006-03-07
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase.
Bmc Struct.Biol., 8, 2008
2HH9
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THIAMIN PYROPHOSPHOKINASE FROM CANDIDA ALBICANS
Descriptor:Thiamin pyrophosphokinase, MAGNESIUM ION, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Authors:Abergel, C., Santini, S., Monchois, V., Rousselle, T., Claverie, J.M., Bacterial targets at IGS-CNRS, France (BIGS)
Deposit date:2006-06-28
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase.
Bmc Struct.Biol., 8, 2008
4R61
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CRYSTAL STRUCTURE OF A RATIONALLY DESIGNED SINGLE-CHAIN PROTEIN MIMICKING A TRIMERIC GP41 N-TERMINAL HEPTAD-REPEAT REGION
Descriptor:gp41-based construct covNHR3-ABC
Authors:Camara-Artigas, A., Conejero-Lara, F., Crespillo, S., Casares, S.
Deposit date:2014-08-22
Release date:2014-12-10
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
2C5W
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PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PENICILLIN-BINDING PROTEIN 1A, ZINC ION, CHLORIDE ION, ...
Authors:Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2005-11-02
Release date:2005-12-07
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
2C6W
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PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:PENICILLIN-BINDING PROTEIN 1A, ZINC ION, CHLORIDE ION
Authors:Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2005-11-14
Release date:2005-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
6R2G
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CRYSTAL STRUCTURE OF A SINGLE-CHAIN PROTEIN MIMETIC OF THE GP41 NHR TRIMER IN COMPLEX WITH THE SYNTHETIC CHR PEPTIDE C34
Descriptor:Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41, Envelope glycoprotein gp160, PHOSPHATE ION
Authors:Camara-Artigas, A., Conejero-Lara, F., Jurado, S., Cano-Munoz, M., Morel, B.
Deposit date:2019-03-17
Release date:2019-07-10
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins.
J.Mol.Biol., 431, 2019