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4R61

Crystal structure of a rationally designed single-chain protein mimicking a trimeric gp41 N-terminal heptad-repeat region

Summary for 4R61
Entry DOI10.2210/pdb4r61/pdb
Descriptorgp41-based construct covNHR3-ABC (1 entity in total)
Functional Keywordscoiled-coil, viral protein
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains1
Total formula weight20265.14
Authors
Camara-Artigas, A.,Conejero-Lara, F.,Crespillo, S.,Casares, S. (deposition date: 2014-08-22, release date: 2014-12-10, Last modification date: 2023-09-20)
Primary citationCrespillo, S.,Camara-Artigas, A.,Casares, S.,Morel, B.,Cobos, E.S.,Mateo, P.L.,Mouz, N.,Martin, C.E.,Roger, M.G.,El Habib, R.,Su, B.,Moog, C.,Conejero-Lara, F.
Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs.
Proc.Natl.Acad.Sci.USA, 111:18207-18212, 2014
Cited by
PubMed: 25489108
DOI: 10.1073/pnas.1413592112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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