4R61
Crystal structure of a rationally designed single-chain protein mimicking a trimeric gp41 N-terminal heptad-repeat region
Summary for 4R61
Entry DOI | 10.2210/pdb4r61/pdb |
Descriptor | gp41-based construct covNHR3-ABC (1 entity in total) |
Functional Keywords | coiled-coil, viral protein |
Biological source | Human immunodeficiency virus 1 (HIV-1) |
Total number of polymer chains | 1 |
Total formula weight | 20265.14 |
Authors | Camara-Artigas, A.,Conejero-Lara, F.,Crespillo, S.,Casares, S. (deposition date: 2014-08-22, release date: 2014-12-10, Last modification date: 2023-09-20) |
Primary citation | Crespillo, S.,Camara-Artigas, A.,Casares, S.,Morel, B.,Cobos, E.S.,Mateo, P.L.,Mouz, N.,Martin, C.E.,Roger, M.G.,El Habib, R.,Su, B.,Moog, C.,Conejero-Lara, F. Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs. Proc.Natl.Acad.Sci.USA, 111:18207-18212, 2014 Cited by PubMed: 25489108DOI: 10.1073/pnas.1413592112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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