1K25

PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate

Summary for 1K25

Entry DOI	10.2210/pdb1k25/pdb
Related	1QME 1QMF
Descriptor	low-affinity PENICILLIN-BINDING PROTEIN 2X (2 entities in total)
Functional Keywords	antibiotic resistance, clinical mutant, low-affinity penicillin-binding, membrane protein
Biological source	Streptococcus pneumoniae
Total number of polymer chains	4
Total formula weight	301037.72
Authors	Dessen, A.,Mouz, N.,Hopkins, J.,Dideberg, O. (deposition date: 2001-09-26, release date: 2001-10-31, Last modification date: 2024-02-07)
Primary citation	Dessen, A.,Mouz, N.,Gordon, E.,Hopkins, J.,Dideberg, O. Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations. J.Biol.Chem., 276:45106-45112, 2001 Cited by PubMed: 11553637 DOI: 10.1074/jbc.M107608200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation