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6KEL
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CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN APO-FORM
Descriptor:Glutathione S-transferase E14, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Senda, T., Niwa, R.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
6KEM
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CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN APO-FORM 2
Descriptor:Glutathione S-transferase E14
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
6KEN
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CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN GLUTATHIONE-BOUND FORM
Descriptor:Glutathione S-transferase E14, GLUTATHIONE
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
6KEO
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CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN 17BETA-ESTRADIOL-BOUND FORM
Descriptor:Glutathione S-transferase E14, ESTRADIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Integrative in silico, in vitro, and in vivo approach unravels an essential amino acid for the function of the insect steroidgenic regulator.
To Be Published
6KEP
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CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN 17BETA-ESTRADIOL- AND GLUTATHIONE-BOUND FORM
Descriptor:Glutathione S-transferase E14, GLUTATHIONE, ESTRADIOL
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
6KEQ
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CRYSTAL STRUCTURE OF D113A MUTANT OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN APO-FORM
Descriptor:Glutathione S-transferase E14
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
6KER
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CRYSTAL STRUCTURE OF D113A MUTANT OF DROSOPHILA MELANOGASTER NOPPERA-BO, GLUTATHIONE S-TRANSFERASE EPSILON 14 (DMGSTE14), IN GLUTATHIONE-BOUND FORM
Descriptor:Glutathione S-transferase E14, GLUTATHIONE
Authors:Koiwai, K., Inaba, K., Morohashi, K., Yumoto, F., Niwa, R., Senda, T.
Deposit date:2019-07-04
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Integrative in silico, in vitro, and in vivo functional analysis of the insect steroidgenic regulator, noppera-bo.
To Be Published
2L84
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SOLUTION NMR STRUCTURES OF CBP BROMODOMAIN WITH SMALL MOLECULE J28
Descriptor:CREB-binding protein, 5-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid
Authors:Borah, J.C., Mujtaba, S., Karakikes, I., Zeng, L., Muller, M., Patel, J., Moshkina, N., Morohashi, K., Zhang, W., Gerona-Navarro, G., Hajjar, R.J., Zhou, M.
Deposit date:2011-01-03
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes.
Chem.Biol., 18, 2011
2L85
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SOLUTION NMR STRUCTURES OF CBP BROMODOMAIN WITH SMALL MOLECULE OF HBS
Descriptor:CREB-binding protein, 4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid
Authors:Borah, J.C., Mujtaba, S., Karakikes, I., Zeng, L., Muller, M., Patel, J., Moshkina, N., Morohashi, K., Zhang, W., Gerona-Navarro, G., Hajjar, R.J., Zhou, M.
Deposit date:2011-01-04
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes.
Chem.Biol., 18, 2011
3W3E
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STRUCTURE OF VIGNA UNGUICULATA CHITINASE WITH REGULATION ACTIVITY OF THE PLANT CELL WALL
Descriptor:Cotyledoneous yieldin-like protein
Authors:Morohashi, K., Sasaki, K., Sakabe, N., Sakabe, K.
Deposit date:2012-12-20
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structure analysis of Vigna unguiculata chitinase with regulation activity of the yield threshold of cell wall
To be Published
4NUC
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH MS435 INHIBITOR
Descriptor:Bromodomain-containing protein 4, 4-[(E)-(4-hydroxy-3,5-dimethylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, 1,2-ETHANEDIOL
Authors:Plotnikov, A.N., Joshua, J., Zhou, M.-M.
Deposit date:2013-12-03
Release date:2014-04-02
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
4NUD
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH MS436 INHIBITOR
Descriptor:Bromodomain-containing protein 4, 4-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, 1,2-ETHANEDIOL
Authors:Plotnikov, A.N., Joshua, J., Zhou, M.-M.
Deposit date:2013-12-03
Release date:2014-04-02
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
4NUE
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH MS267 INHIBITOR
Descriptor:Bromodomain-containing protein 4, 4-[(E)-(2-amino-4-hydroxy-3,5-dimethylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, 1,2-ETHANEDIOL
Authors:Plotnikov, A.N., Joshua, J., Zhou, M.-M.
Deposit date:2013-12-03
Release date:2014-04-02
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
4X3K
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CRYSTAL STRUCTURE OF CHROMOBOX HOMOLOG 7 (CBX7) CHROMODOMAIN WITH H3K27ME3 PEPTIDE
Descriptor:Chromobox protein homolog 7, H3K27me3 peptide, NICKEL (II) ION, ...
Authors:Ren, C., Zhou, M.M.
Deposit date:2014-12-01
Release date:2015-03-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015
4X3S
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CRYSTAL STRUCTURE OF CHROMOBOX HOMOLOGY 7 (CBX7) WITH SETDB1-1170ME3 PEPTIDE
Descriptor:Chromobox protein homolog 7, SETDB1-1170me3 Peptide, FE (III) ION, ...
Authors:Ren, C., Plotnikov, A.N., Zhou, M.M.
Deposit date:2014-12-01
Release date:2015-03-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015
4X3T
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CRYSTAL STRUCTURE OF CHROMOBOX HOMOLOG 7 (CBX7) CHROMODOMAIN WITH MS37452
Descriptor:Chromobox protein homolog 7, 1-[4-(2,3-dimethoxybenzoyl)piperazin-1-yl]-2-(3-methylphenoxy)ethanone, ZINC ION, ...
Authors:Ren, C., Jakoncic, J., Zhou, M.M.
Deposit date:2014-12-01
Release date:2015-03-04
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015
4X3U
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CRYSTAL STRUCTURE OF CHROMOBOX HOMOLOG 7 (CBX7) CHROMODOMAIN WITH SURAMIN
Descriptor:Chromobox protein homolog 7, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID
Authors:Ren, C., Zhou, M.M.
Deposit date:2014-12-01
Release date:2015-03-04
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015