4X3T
Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS37452
Summary for 4X3T
Entry DOI | 10.2210/pdb4x3t/pdb |
Related | 4X3S 4X3U |
Descriptor | Chromobox protein homolog 7, 1-[4-(2,3-dimethoxybenzoyl)piperazin-1-yl]-2-(3-methylphenoxy)ethanone, ZINC ION, ... (5 entities in total) |
Functional Keywords | cbx7, chromodomain, ms37452, inhibitor, transcription |
Biological source | Mus musculus (Mouse) |
Cellular location | Nucleus : Q8VDS3 |
Total number of polymer chains | 6 |
Total formula weight | 49426.72 |
Authors | Ren, C.,Jakoncic, J.,Zhou, M.M. (deposition date: 2014-12-01, release date: 2015-03-04, Last modification date: 2024-02-28) |
Primary citation | Ren, C.,Morohashi, K.,Plotnikov, A.N.,Jakoncic, J.,Smith, S.G.,Li, J.,Zeng, L.,Rodriguez, Y.,Stojanoff, V.,Walsh, M.,Zhou, M.M. Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22:161-168, 2015 Cited by PubMed: 25660273DOI: 10.1016/j.chembiol.2014.11.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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