2L84
Solution NMR structures of CBP bromodomain with small molecule j28
Summary for 2L84
Entry DOI | 10.2210/pdb2l84/pdb |
NMR Information | BMRB: 17392 |
Descriptor | CREB-binding protein, 5-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid (2 entities in total) |
Functional Keywords | p53, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q92793 |
Total number of polymer chains | 1 |
Total formula weight | 14753.93 |
Authors | Borah, J.C.,Mujtaba, S.,Karakikes, I.,Zeng, L.,Muller, M.,Patel, J.,Moshkina, N.,Morohashi, K.,Zhang, W.,Gerona-Navarro, G.,Hajjar, R.J.,Zhou, M. (deposition date: 2011-01-03, release date: 2011-01-19, Last modification date: 2011-07-13) |
Primary citation | Borah, J.C.,Mujtaba, S.,Karakikes, I.,Zeng, L.,Muller, M.,Patel, J.,Moshkina, N.,Morohashi, K.,Zhang, W.,Gerona-Navarro, G.,Hajjar, R.J.,Zhou, M.M. A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes. Chem.Biol., 18:531-541, 2011 Cited by PubMed: 21513889DOI: 10.1016/j.chembiol.2010.12.021 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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