2L84

Solution NMR structures of CBP bromodomain with small molecule j28

Spectrometer

Experimental method: SOLUTION NMR

Spectrometer ID	Spectrometer maker	Spectrometer model	Spectrometer type	Spectrometer field strength
1	Bruker	AVANCE	Bruker Avance	900
2	Bruker	AVANCE	Bruker Avance	800
3	Bruker	AVANCE	Bruker Avance	600
4	Bruker	DRX	Bruker DRX	500

Experiment

experiment id	conditions id	solution id	Experiment type
1	1	1	3D HNCACB
2	1	1	3D HN(COCA)CB
3	1	1	3D 1H-15N NOESY
4	1	2	3D 1H-13C NOESY aliphatic
5	1	2	3D 1H-13C NOESY aromatic
6	1	2	3D 13C-edited 13C/15N-filtered NOESY

NMR Sample

conditions id	NMR sample pH	NMR sample pressure	NMR sample temperature
1	6.5	ambient	298

Conformers

Conformers Calculated Total Number	200
Conformers Submitted Total Number	20