Author results

1PFL
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REFINED SOLUTION STRUCTURE OF HUMAN PROFILIN I
Descriptor:PROFILIN I
Authors:Metzler, W.J., Farmer II, B.T., Constantine, K.L., Friedrichs, M.S., Lavoie, T., Mueller, L.
Deposit date:1994-12-12
Release date:1995-03-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined solution structure of human profilin I.
Protein Sci., 4, 1995
1AH1
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CTLA-4, NMR, 20 STRUCTURES
Descriptor:CTLA-4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Metzler, W.J., Bajorath, J., Fenderson, W., Shaw, S.-Y., Peach, R., Constantine, K.L., Naemura, J., Leytze, G., Lavoie, T.B., Mueller, L., Linsley, P.S.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28.
Nat.Struct.Biol., 4, 1997
1BLJ
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NMR ENSEMBLE OF BLK SH2 DOMAIN, 20 STRUCTURES
Descriptor:P55 BLK PROTEIN TYROSINE KINASE
Authors:Metzler, W.J., Leiting, B., Pryor, K., Mueller, L., Farmer II, B.T.
Deposit date:1996-03-26
Release date:1997-03-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The three-dimensional solution structure of the SH2 domain from p55blk kinase.
Biochemistry, 35, 1996
1BLK
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NMR ENSEMBLE OF BLK SH2 DOMAIN USING CHEMICAL SHIFT REFINEMENT, 20 STRUCTURES
Descriptor:P55 BLK PROTEIN TYROSINE KINASE
Authors:Metzler, W.J., Leiting, B., Pryor, K., Mueller, L., Farmer II, B.T.
Deposit date:1996-03-26
Release date:1997-03-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The three-dimensional solution structure of the SH2 domain from p55blk kinase.
Biochemistry, 35, 1996
1AKP
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SEQUENTIAL 1H,13C AND 15N NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF APOKEDARCIDIN
Descriptor:APOKEDARCIDIN
Authors:Constantine, K.L., Colson, K.L., Wittekind, M., Friedrichs, M.S., Zein, N., Tuttle, J., Langley, D.R., Leet, J.E., Schroeder, D.R., Lam, K.S., Farmer II, B.T., Metzler, W.J., Bruccoleri, R.E., Mueller, L.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential 1H, 13C, and 15N NMR assignments and solution conformation of apokedarcidin.
Biochemistry, 33, 1994
1MAJ
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SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN
Descriptor:IGG2A-KAPPA 26-10 FV (LIGHT CHAIN)
Authors:Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L.
Deposit date:1993-09-16
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
1MAK
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SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN
Descriptor:IGG2A-KAPPA 26-10 FV (LIGHT CHAIN)
Authors:Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L.
Deposit date:1993-09-16
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of an isolated antibody VL domain.
J.Mol.Biol., 236, 1994
3BJM
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CRYSTAL STRUCTURE OF HUMAN DPP-IV IN COMPLEX WITH (1S,3S, 5S)-2-[(2S)-2-AMINO-2-(3-HYDROXYTRICYCLO[3.3.1.13,7]DEC-1- YL)ACETYL]-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (CAS), (1S,3S,5S)-2-((2S)-2-AMINO-2-(3-HYDROXYADAMANTAN-1- YL)ACETYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (IUPAC), OR BMS-477118
Descriptor:Dipeptidyl peptidase 4, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2~{S})-2-azanyl-1-[(1~{S},3~{S},5~{S})-3-(iminomethyl)-2-azabicyclo[3.1.0]hexan-2-yl]-2-[(5~{R},7~{S})-3-oxidanyl-1-ad amantyl]ethanone
Authors:Klei, H.E.
Deposit date:2007-12-04
Release date:2008-04-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation.
Protein Sci., 17, 2008
4KNV
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THE CRYSTAL STRUCTURE OF APO HUMAN HDHD4 FROM SE-MAD
Descriptor:N-acylneuraminate-9-phosphatase, PHOSPHATE ION, MAGNESIUM ION
Authors:Klei, H.E.
Deposit date:2013-05-10
Release date:2013-06-26
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.993 Å)
Cite:Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex.
Bioorg.Med.Chem.Lett., 23, 2013
4KNW
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THE CRYSTAL STRUCTURE OF HUMAN HDHD4 IN COMPLEX WITH MAGNESIUM AND THE PHOSPHATE MIMETIC VANADATE
Descriptor:N-acylneuraminate-9-phosphatase, VANADATE ION, MAGNESIUM ION
Authors:Klei, H.E.
Deposit date:2013-05-10
Release date:2013-06-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex.
Bioorg.Med.Chem.Lett., 23, 2013
4X8S
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FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 4-BROMO-2-METHOXYPHENOL
Descriptor:Factor VIIa (Heavy Chain), Factor VIIa (Light Chain), 4-bromo-2-methoxyphenol, ...
Authors:Wei, A.
Deposit date:2014-12-10
Release date:2015-03-25
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
J.Med.Chem., 58, 2015
4X8T
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FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-CHLORO-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE
Descriptor:Factor VIIa (Heavy Chain), Factor VIIa (Light Chain), 7-chloro-3,4-dihydroisoquinolin-1(2H)-one, ...
Authors:Wei, A.
Deposit date:2014-12-10
Release date:2015-03-25
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
J.Med.Chem., 58, 2015
4X8U
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FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID
Descriptor:Factor VIIa (Heavy Chain), Factor VIIa (Light Chain), 5-chloro-1H-indole-2-carboxylic acid, ...
Authors:Wei, A.
Deposit date:2014-12-10
Release date:2015-03-25
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
J.Med.Chem., 58, 2015
4X8V
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FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (METHYL {3-[(2R)-1-{(2R)-2-(3,4-DIMETHOXYPHENYL)-2-[(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)AMINO]ACETYL}PYRROLIDIN-2-YL]-4-(PROPAN-2-YLSULFONYL)PHENYL}CARBAMATE)
Descriptor:Factor VIIa (Heavy Chain), Factor VIIa (Light Chain), methyl {3-[(2R)-1-{(2R)-2-(3,4-dimethoxyphenyl)-2-[(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]acetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}carbamate, ...
Authors:Wei, A.
Deposit date:2014-12-10
Release date:2015-03-25
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
J.Med.Chem., 58, 2015
1BBG
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RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:POLLEN ALLERGEN 5
Authors:Warren, G.L., Tuner, C.J., Petsko, G.A., Brunger, A.T.
Deposit date:1998-04-24
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
2BBG
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RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, 30 STRUCTURES
Descriptor:POLLEN ALLERGEN 5
Authors:Warren, G.L., Tuner, C.J., Petsko, G.A., Brunger, A.T.
Deposit date:1998-04-24
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
3BBG
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MULTI-CONFORMER STRUCTURE OF RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, 2 STRUCTURES
Descriptor:POLLEN ALLERGEN 5
Authors:Warren, G.L., Tuner, C.J., Petsko, G.A., Brunger, A.T.
Deposit date:1998-04-24
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
3QCB
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, APO
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCC
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH VANADATE, ORTHORHOMBIC CRYSTAL FORM
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, VANADATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCD
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH VANADATE, TRIGONAL CRYSTAL FORM
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, VANADATE ION, ACETIC ACID
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCE
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH 3-[(3,4-DICHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXYLIC ACID VIA SOAKING
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, SULFATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCF
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH 3-[(3,4-DICHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXYLIC ACID VIA CO-CRYSTALLIZATION
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, SULFATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCG
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH 3-[(3-BROMO-4-CHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXYLIC ACID
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, ACETIC ACID
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCH
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH 3-[(3,4-DICHLOROBENZYL)SULFANYL]-N-(METHYLSULFONYL)THIOPHENE-2-CARBOXAMIDE
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, 3-[(3,4-dichlorobenzyl)sulfanyl]-N-(methylsulfonyl)thiophene-2-carboxamide
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCI
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HUMAN RECEPTOR PROTEIN TYROSINE PHOSPHATASE GAMMA, DOMAIN 1, IN COMPLEX WITH N-[(3-AMINOPHENYL)SULFONYL]-3-[(3,4-DICHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXAMIDE
Descriptor:Receptor-type tyrosine-protein phosphatase gamma, N-[(3-aminophenyl)sulfonyl]-3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxamide
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
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170172
PDB entries from 2020-10-21