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6VG3
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BU of 6vg3 by Molmil
Structure of unliganded, inactive PTK7 kinase domain
Descriptor: Inactive tyrosine-protein kinase 7
Authors:Malhotra, K, Stayrook, S.E, Sheetz, J, Lemmon, M.A.
Deposit date:2020-01-07
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into receptor tyrosine kinase pseudokinase function
Mol.Cell, 2020
7QWJ
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BU of 7qwj by Molmil
Crystal structure of Glc7 phosphatase
Descriptor: MANGANESE (II) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase PP1-2
Authors:Malhotra, K, Carminati, M, Bertolotti, A, Bellini, D.
Deposit date:2022-01-25
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Glc7 phosphatase
To Be Published
3P9N
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BU of 3p9n by Molmil
Rv2966c of M. tuberculosis is a RsmD-like methyltransferase
Descriptor: ACETATE ION, POSSIBLE METHYLTRANSFERASE (METHYLASE)
Authors:Kumar, A, Malhotra, K, Saigal, K, Sinha, K.M, Taneja, B.
Deposit date:2010-10-18
Release date:2011-04-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition
J.Biol.Chem., 286, 2011
5WNO
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BU of 5wno by Molmil
Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Receptor tyrosine-protein kinase let-23
Authors:Liu, L, Thaker, T.M, Jura, N.
Deposit date:2017-08-01
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.
Structure, 26, 2018
6TU9
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BU of 6tu9 by Molmil
The ROR1 Pseudokinase Domain Bound To Ponatinib
Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Inactive tyrosine-protein kinase transmembrane receptor ROR1
Authors:Mathea, S, Preuss, F, Chatterjee, D, Niininen, W, Ungureanu, D, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
Deposit date:2020-01-04
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020
6TUA
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BU of 6tua by Molmil
The RYK Pseudokinase Domain
Descriptor: SULFATE ION, Tyrosine-protein kinase RYK
Authors:Mathea, S, Chatterjee, D, Preuss, F, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
Deposit date:2020-01-04
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020
8TBQ
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BU of 8tbq by Molmil
The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of pH-selective anti-VISTA antibody
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SNS-101 Fab heavy chain, ...
Authors:van der Horst, E.H, Mukherjee, A, Thisted, T.
Deposit date:2023-06-29
Release date:2024-03-20
Method:X-RAY DIFFRACTION (2.593 Å)
Cite:The pH-selective anti-VISTA antibody SNS-101 displays a favorable pharmacokinetic and safety profile and promotes anti-tumoral M1 macrophage polarization in PD-1 refractory settings
To Be Published

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PDB entries from 2024-09-18

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