6VG3
Structure of unliganded, inactive PTK7 kinase domain
Summary for 6VG3
Entry DOI | 10.2210/pdb6vg3/pdb |
Descriptor | Inactive tyrosine-protein kinase 7 (2 entities in total) |
Functional Keywords | kinase, pseudokinase, autoinhibition, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 99851.99 |
Authors | Malhotra, K.,Stayrook, S.E.,Sheetz, J.,Lemmon, M.A. (deposition date: 2020-01-07, release date: 2020-05-27, Last modification date: 2023-10-11) |
Primary citation | Sheetz, J.B.,Mathea, S.,Karvonen, H.,Malhotra, K.,Chaterjee, D.,Perttila, R.,Niininen, W.,Stayrook, S.E.,Radhakrishnan, R.,Ungureanu, D.,Knapp, S.,Lemmon, M.A. Structural insights into receptor tyrosine kinase pseudokinase function Mol.Cell, 2020 |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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