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2G62
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CRYSTAL STRUCTURE OF HUMAN PTPA
Descriptor:protein phosphatase 2A, regulatory subunit B' (PR 53), SULFATE ION, ...
Authors:Magnusdottir, A., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Hogbom, M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-02-24
Release date:2006-04-04
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of a human PP2A phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions.
J.Biol.Chem., 281, 2006
2JAK
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HUMAN PP2A REGULATORY SUBUNIT B56G
Descriptor:SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM
Authors:Magnusdottir, A., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Lundgren, S., Moche, M., Nilsson, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.
Deposit date:2006-11-29
Release date:2006-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of the Pp2A Regulatory Subunit B56 Gamma: The Remaining Piece of the Pp2A Jigsaw Puzzle.
Proteins, 74, 2009
2J91
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CRYSTAL STRUCTURE OF HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH AMP
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-11-01
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human Adenylosuccinate Lyase
To be Published
2UW2
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE SUBUNIT R2
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT, FE (III) ION
Authors:Welin, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Stenmark, P., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2I4I
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CRYSTAL STRUCTURE OF HUMAN DEAD-BOX RNA HELICASE DDX3X
Descriptor:ATP-dependent RNA helicase DDX3X, ADENOSINE MONOPHOSPHATE
Authors:Hogbom, M., Karlberg, T., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-08-22
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
J.Mol.Biol., 372, 2007
2NZ2
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CRYSTAL STRUCTURE OF HUMAN ARGININOSUCCINATE SYNTHASE IN COMPLEX WITH ASPARTATE AND CITRULLINE
Descriptor:Argininosuccinate synthase, SODIUM ION, ASPARTIC ACID, ...
Authors:Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-11-22
Release date:2006-12-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human argininosuccinate synthetase.
Acta Crystallogr.,Sect.D, 64, 2008
2CL3
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CRYSTAL STRUCTURE OF HUMAN CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (CPSF5)
Descriptor:CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5
Authors:Stenmark, P., Hogbom, M., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-04-25
Release date:2006-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.
Proteins, 73, 2008
2CN1
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE III (NT5C3)(CASP TARGET)
Descriptor:CYTOSOLIC 5'-NUCLEOTIDASE III
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-05-17
Release date:2006-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition.
J.Biol.Chem., 282, 2007
2J2C
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II (NT5C2, CN-II)
Descriptor:CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, SULFATE ION, ...
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Karlberg, T., Kotenyova, T., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-08-16
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2J4E
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THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
Descriptor:INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmbergschiavone, L., Hogbom, M., Kotenyova, T., Landry, R., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Schuler, H., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-08-29
Release date:2006-09-20
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
2J67
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THE TIR DOMAIN OF HUMAN TOLL-LIKE RECEPTOR 10 (TLR10)
Descriptor:TOLL LIKE RECEPTOR 10
Authors:Stenmark, P., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-09-26
Release date:2006-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283, 2008
2J8Q
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CRYSTAL STRUCTURE OF HUMAN CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (CPSF5) IN COMPLEX WITH A SULPHATE ION.
Descriptor:CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5, SULFATE ION
Authors:Moche, M., Stenmark, P., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg, S.L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-10-27
Release date:2006-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.
Proteins, 73, 2008
2JC9
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH ADENOSINE
Descriptor:CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ...
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg, S.L., Hogbom, M., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Loppnau, P., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-12-21
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2JCM
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH BERYLLIUM TRIFLUORIDE
Descriptor:CYTOSOLIC PURINE 5'-NUCLEOTIDASE, UNKNOWN ATOM OR ION, MAGNESIUM ION, ...
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Loppnau, P., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2006-12-27
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2JGA
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE III IN COMPLEX WITH PHOSPHATE AND MAGNESIUM
Descriptor:CYTOSOLIC 5'-NUCLEOTIDASE III, PHOSPHATE ION, MAGNESIUM ION
Authors:Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, M., Holmberg, B., Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2007-02-09
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition.
J.Biol.Chem., 282, 2007
2NMP
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CRYSTAL STRUCTURE OF HUMAN CYSTATHIONINE GAMMA LYASE
Descriptor:Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van-den-Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-10-23
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
3R44
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MYCOBACTERIUM TUBERCULOSIS FATTY ACYL COA SYNTHETASE
Descriptor:fatty acyl CoA synthetase FADD13 (FATTY-ACYL-CoA SYNTHETASE), HISTIDINE, MALONATE ION
Authors:Andersson, C.S., Martinez Molina, D., Hogbom, M.
Deposit date:2011-03-17
Release date:2012-02-08
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Mycobacterium tuberculosis Very-Long-Chain Fatty Acyl-CoA Synthetase: Structural Basis for Housing Lipid Substrates Longer than the Enzyme.
Structure, 20, 2012