Author results

6UZZ
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STRUCTURE OF HUMAN KCNQ1-CAM COMPLEX
分子名称:Potassium voltage-gated channel subfamily KQT member 1, Calmodulin-1, CALCIUM ION
著者Mackinnon, R., Sun, J.
登録日2019-11-16
公開日2019-12-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of human KCNQ1 modulation and gating
To Be Published
6V00
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STRUCTURE OF HUMAN KCNQ1-KCNE3-CAM COMPLEX
分子名称:Potassium voltage-gated channel subfamily KQT member 1, Calmodulin-1, MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3, ...
著者Mackinnon, R., Sun, J.
登録日2019-11-16
公開日2019-12-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of human KCNQ1 modulation and gating
To Be Published
6V01
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STRUCTURE OF HUMAN KCNQ1-KCNE3-CAM COMPLEX WITH PIP2
分子名称:Calmodulin-1, Potassium voltage-gated channel subfamily E member 3,Potassium voltage-gated channel subfamily E member 3, Potassium voltage-gated channel subfamily KQT member 1, ...
著者Mackinnon, R., Sun, J.
登録日2019-11-18
公開日2019-12-04
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of human KCNQ1 modulation and gating
To Be Published
1S5H
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POTASSIUM CHANNEL KCSA-FAB COMPLEX T75C MUTANT IN K+
分子名称:ANTIBODY FAB FRAGMENT LIGHT CHAIN, ANTIBODY FAB FRAGMENT HEAVY CHAIN, Voltage-gated potassium channel, ...
著者Mackinnon, R., Zhou, M.
登録日2004-01-20
公開日2004-05-18
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
J.Mol.Biol., 338, 2004
4JTA
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CRYSTAL STRUCTURE OF KV1.2-2.1 PADDLE CHIMERA CHANNEL IN COMPLEX WITH CHARYBDOTOXIN
分子名称:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2, Potassium voltage-gated channel subfamily B member 1, ...
著者MacKinnon, R., Banerjee, A., Lee, A., Campbell, E.
登録日2013-03-23
公開日2013-06-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
5TJ6
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CA2+ BOUND APLYSIA SLO1
分子名称:High conductance calcium-activated potassium channel, POTASSIUM ION, MAGNESIUM ION, ...
著者MacKinnon, R., Tao, X., Hite, R.K.
登録日2016-10-03
公開日2016-12-14
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
5TJI
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CA2+ BOUND APLYSIA SLO1
分子名称:High conductance calcium-activated potassium channel, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
著者MacKinnon, R., Tao, X., Hite, R.K.
登録日2016-10-04
公開日2016-12-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for gating the high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
5VMS
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CRYOEM STRUCTURE OF XENOPUS KCNQ1 CHANNEL
分子名称:Potassium voltage-gated channel subfamily KQT member 1, Calmodulin, CALCIUM ION
著者Mackinnon, R., Sun, J.
登録日2017-04-28
公開日2017-06-07
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Cell, 169, 2017
1LNQ
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CRYSTAL STRUCTURE OF MTHK AT 3.3 A
分子名称:POTASSIUM CHANNEL RELATED PROTEIN, CALCIUM ION
著者Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., Mackinnon, R.
登録日2002-05-03
公開日2002-06-19
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
2A79
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MAMMALIAN SHAKER KV1.2 POTASSIUM CHANNEL- BETA SUBUNIT COMPLEX
分子名称:Voltage-gated potassium channel beta-2 subunit, Potassium voltage-gated channel subfamily A member 2, poly-unknown chain, ...
著者Long, S.B., Campbell, E.B., MacKinnon, R.
登録日2005-07-05
公開日2005-07-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.
Science, 309, 2005
2R9R
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SHAKER FAMILY VOLTAGE DEPENDENT POTASSIUM CHANNEL (KV1.2-KV2.1 PADDLE CHIMERA CHANNEL) IN ASSOCIATION WITH BETA SUBUNIT
分子名称:Voltage-gated potassium channel subunit beta-2, Paddle chimera voltage gated potassium channel Kv1.2-Kv2.1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Long, S.B., Tao, X., Campbell, E.B., Mackinnon, R.
登録日2007-09-13
公開日2007-11-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
Nature, 450, 2007
1KPK
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CRYSTAL STRUCTURE OF THE CLC CHLORIDE CHANNEL FROM E. COLI
分子名称:putative channel transporter
著者Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2001-12-31
公開日2002-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1KPL
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CRYSTAL STRUCTURE OF THE CLC CHLORIDE CHANNEL FROM S. TYPHIMURIUM
分子名称:putative ClC family, chlorine transport protein, CHLORIDE ION, ...
著者Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2001-12-31
公開日2002-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1OTS
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL AND FAB COMPLEX
分子名称:Voltage-gated ClC-type chloride channel eriC, Fab fragment (heavy chain), Fab fragment (light chain), ...
著者Dutzler, R., Campbell, E.B., MacKinnon, R.
登録日2003-03-22
公開日2003-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
1OTT
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL E148A MUTANT AND FAB COMPLEX
分子名称:Voltage-gated ClC-type chloride channel eriC, Fab fragment (Heavy chain), Fab fragment (Light chain), ...
著者Dutzler, R., Campbell, E.B., MacKinnon, R.
登録日2003-03-23
公開日2003-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
1OTU
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL E148Q MUTANT AND FAB COMPLEX
分子名称:Voltage-gated ClC-type chloride channel eriC, Fab fragment (Heavy chain), Fab fragment (Light chain), ...
著者Dutzler, R., Campbell, E.B., MacKinnon, R.
登録日2003-03-23
公開日2003-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
1AGT
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SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY
分子名称:AGITOXIN 2
著者Krezel, A.M., Kasibhatla, C., Hidalgo, P., Mackinnon, R., Wagner, G.
登録日1995-04-14
公開日1995-07-10
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Protein Sci., 4, 1995
1BE9
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THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
分子名称:PSD-95, CRIPT
著者Doyle, D.A., Lee, A., Lewis, J., Kim, E., Sheng, M., Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1BFE
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THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
分子名称:PSD-95
著者Doyle, D.A., Lee, A., Lewis, J., Kim, E., Sheng, M., Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1BL8
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POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS
分子名称:PROTEIN (POTASSIUM CHANNEL PROTEIN), POTASSIUM ION
著者Doyle, D.A., Cabral, J.M., Pfuetzner, R.A., Kuo, A., Gulbis, J.M., Cohen, S.L., Chait, B.T., Mackinnon, R.
登録日1998-07-23
公開日1998-07-29
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structure of the potassium channel: molecular basis of K+ conduction and selectivity.
Science, 280, 1998
1BYW
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STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN-ERG POTASSIUM CHANNEL
分子名称:PROTEIN (HUMAN ERG POTASSIUM CHANNEL)
著者Cabral, J.H.M., Lee, A., Mackinnon, R.
登録日1998-10-15
公開日1998-12-16
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure and Functional Analysis of the Herg Potassium Channel N-Terminus: A Eukaryotic Pas Domain
Cell(Cambridge,Mass.), 95, 1998
1EXB
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STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS
分子名称:KV BETA2 PROTEIN, POTASSIUM CHANNEL KV1.1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Gulbis, J.M., Zhou, M., Mann, S., MacKinnon, R.
登録日2000-05-02
公開日2000-07-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.
Science, 289, 2000
1ID1
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CRYSTAL STRUCTURE OF THE RCK DOMAIN FROM E.COLI POTASSIUM CHANNEL
分子名称:PUTATIVE POTASSIUM CHANNEL PROTEIN
著者Jiang, Y., Pico, A., Cadene, M., Chait, B.T., MacKinnon, R.
登録日2001-04-02
公開日2001-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.
Neuron, 29, 2001
1J95
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KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND POTASSIUM
分子名称:VOLTAGE-GATED POTASSIUM CHANNEL, POTASSIUM ION, TETRABUTYLAMMONIUM ION
著者Morais-Cabral, J.H., MacKinnon, R., Zhou, M.
登録日2001-05-23
公開日2001-06-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
Nature, 411, 2001
1JVM
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KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND RUBIDIUM
分子名称:Voltage-gated potassium channel, RUBIDIUM ION, TETRABUTYLAMMONIUM ION
著者Morais-Cabral, J.H., Zhou, Y., MacKinnon, R.
登録日2001-08-30
公開日2001-12-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Energetic optimization of ion conduction rate by the K+ selectivity filter.
Nature, 414, 2001