6XIT

Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with PIP2

Summary for 6XIT

• Entry DOI: 10.2210/pdb6xit/pdb
• Related: 6XIS
• EMDB information: 22199 22200
• Descriptor: G protein-activated inward rectifier potassium channel 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, POTASSIUM ION (3 entities in total)
• Functional Keywords: g protein-coupled inwardly rectifying potassium channels, pip2, membrane protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 4
• Total formula weight: 159351.39

Authors

Niu, Y.,Tao, X.,MacKinnon, R. (deposition date: 2020-06-21, release date: 2020-10-07)

• Primary citation: Niu, Y.,Tao, X.,Touhara, K.K.,MacKinnon, R.; Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.; Elife, 9:-, 2020; PubMed: 32844743; DOI: 10.7554/eLife.60552

Experimental method

ELECTRON MICROSCOPY (3.3 Å)