6B3R

Structure of the mechanosensitive channel Piezo1

Summary for 6B3R

Entry DOI	10.2210/pdb6b3r/pdb
EMDB information	7042
Descriptor	Piezo-type mechanosensitive ion channel component 1, Piezo-type mechanosensitive ion channel component 1, unknown fragment (2 entities in total)
Functional Keywords	triskelion, transmembrane, ion channel, membrane protein, transport protein
Biological source	Mus musculus (Mouse) More
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein: E2JF22
Total number of polymer chains	6
Total formula weight	881101.04
Authors	Guo, Y.R.,MacKinnon, R. (deposition date: 2017-09-22, release date: 2017-12-20, Last modification date: 2018-05-16)
Primary citation	Guo, Y.R.,MacKinnon, R. Structure-based membrane dome mechanism for Piezo mechanosensitivity. Elife, 6:-, 2017 Cited by PubMed: 29231809 DOI: 10.7554/eLife.33660 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation