Author results

3BJV
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THE CRYSTAL STRUCTURE OF A PUTATIVE PTS IIA(PTXA) FROM STREPTOCOCCUS MUTANS
分子名称:RmpA
著者Lei, J., Liang, Y.H., Su, X.D.
登録日2007-12-04
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of phosphotransferase system enzymes PtxB (IIB(Asc)) and PtxA (IIA(Asc)) from Streptococcus mutans
J.Mol.Biol., 386, 2009
3CZC
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THE CRYSTAL STRUCTURE OF A PUTATIVE PTS IIB(PTXB) FROM STREPTOCOCCUS MUTANS
分子名称:RmpB
著者Lei, J., Su, X.D.
登録日2008-04-29
公開日2009-03-10
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structures of phosphotransferase system enzymes PtxB (IIB(Asc)) and PtxA (IIA(Asc)) from Streptococcus mutans
J.Mol.Biol., 386, 2009
3L8R
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THE CRYSTAL STRUCTURE OF PTCA FROM S. MUTANS
分子名称:Putative PTS system, cellobiose-specific IIA component
著者Lei, J., Liu, X., Li, L.
登録日2010-01-03
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of PtcA from Streptococcus mutans
To be Published
3RK6
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CRYSTAL STRUCTURE OF THE MIDDLE DOMAIN OF HUMAN PAIP1
分子名称:Polyadenylate-binding protein-interacting protein 1
著者Lei, J., Mesters, J.R., Hilgenfeld, R.
登録日2011-04-17
公開日2011-05-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1.
Biochem.Biophys.Res.Commun., 408, 2011
4P16
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CRYSTAL STRUCTURE OF THE PAPAIN-LIKE PROTEASE OF MIDDLE-EAST RESPIRATORY SYNDROME CORONAVIRUS
分子名称:ORF1a, ZINC ION
著者Lei, J., Mesters, J.R., Ma, Q., Hilgenfeld, R.
登録日2014-02-25
公開日2014-05-07
最終更新日2014-08-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features.
Antiviral Res., 109C, 2014
4WUR
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THE CRYSTAL STRUCTURE OF THE MERS-COV PAPAIN-LIKE PROTEASE (C111S) WITH HUMAN UBIQUITIN
分子名称:Papain-like protease, Polyubiquitin-B, ISOPROPYL ALCOHOL, ...
著者Lei, J., Hilgenfeld, R.
登録日2014-11-03
公開日2014-11-26
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
Virol Sin, 31, 2016
5HIH
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CRYSTAL STRUCTURE OF THE MACRO DOMAIN IN MIDDLE-EAST RESPIRATORY SYNDROME CORONAVIRUS
分子名称:ORF1a
著者Lei, J., Hilgenfeld, R.
登録日2016-01-11
公開日2016-01-20
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
Virol Sin, 31, 2016
5HOL
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THE CRYSTAL STRUCTURE OF THE MERS-COV MACRO DOMAIN WITH ADP-RIBOSE
分子名称:ORF1a, ADENOSINE-5-DIPHOSPHORIBOSE
著者Lei, J., Hilgenfeld, R.
登録日2016-01-19
公開日2016-01-27
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.
Antiviral Res., 149, 2018
5LC0
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CRYSTAL STRUCTURE OF ZIKA VIRUS NS2B-NS3 PROTEASE IN COMPLEX WITH A BORONATE INHIBITOR
分子名称:NS2B-NS3 protease,NS2B-NS3 protease, N-((S)-3-(4-(aminomethyl)phenyl)-1-(((R)-4-guanidino-1-(5-hydroxy-1,3,2-dioxaborinan-2-yl)butyl)amino)-1-oxopropan-2-yl)benzamide
著者Lei, J., Hansen, G., Zhang, L.L., Hilgenfeld, R.
登録日2016-06-18
公開日2016-07-06
最終更新日2016-08-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor.
Science, 353, 2016
3D3F
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CRYSTAL STRUCTURE OF YVGN AND COFACTOR NADPH FROM BACILLUS SUBTILIS
分子名称:YvgN protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhou, Y.F., Lei, J., Su, X.D.
登録日2008-05-10
公開日2009-04-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis
Protein Sci., 18, 2009
3F7J
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B.SUBTILIS YVGN
分子名称:YvgN protein, NITRATE ION, POTASSIUM ION
著者Zhou, Y.F., Lei, J., Liang, Y.H., Su, X.-D.
登録日2008-11-09
公開日2008-11-25
最終更新日2014-01-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis
Protein Sci., 18, 2009
5NGN
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LYBATIDE 2, A CYSTINE-RICH PEPTIDE FROM LYCIUM BARBARUM
分子名称:lybatide 2, GLYCEROL, ACETONITRILE, ...
著者Lei, J., Tan, W.L., Sakai, N., Hilgenfeld, R.
登録日2017-03-18
公開日2017-07-26
最終更新日2018-04-11
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold.
Sci Rep, 7, 2017
4CSU
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH OBGE
分子名称:50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, 50S RIBOSOMAL PROTEIN L30, ...
著者Feng, B., Mandava, C.S., Guo, Q., Wang, J., Cao, W., Li, N., Zhang, Y., Zhang, Y., Wang, Z., Wu, J., Sanyal, S., Lei, J., Gao, N.
登録日2014-03-10
公開日2014-06-04
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
4V6K
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STRUCTURAL INSIGHTS INTO COGNATE VS. NEAR-COGNATE DISCRIMINATION DURING DECODING.
分子名称:ribosomal RNA 5S, ribosomal RNA 23S, 50S ribosomal protein L1, ...
著者Agirrezabala, X., Schreiner, E., Trabuco, L.G., Lei, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
登録日2011-01-07
公開日2014-07-09
最終更新日2019-07-03
実験手法ELECTRON MICROSCOPY (8.25 Å)
主引用文献Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
4V6L
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STRUCTURAL INSIGHTS INTO COGNATE VS. NEAR-COGNATE DISCRIMINATION DURING DECODING.
分子名称:16S ribosomal RNA, A/T-site tRNA Phe, Elongation factor Tu 2, ...
著者Agirrezabala, X., Schreiner, E., Trabuco, L.G., Lei, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
登録日2011-01-07
公開日2014-07-09
最終更新日2019-07-03
実験手法ELECTRON MICROSCOPY (13.2 Å)
主引用文献Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
1A94
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STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES
分子名称:PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
登録日1998-04-16
公開日1999-01-13
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
1BAI
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CRYSTAL STRUCTURE OF ROUS SARCOMA VIRUS PROTEASE IN COMPLEX WITH INHIBITOR
分子名称:PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
著者Wu, J., Adomat, J.M., Ridky, T.W., Louis, J.M., Leis, J., Harrison, R.W., Weber, I.T.
登録日1998-04-17
公開日1999-01-13
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
3J3R
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2014-10-22
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3S
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3T
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3U
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
分子名称:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
著者Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
登録日2014-10-24
公開日2014-11-26
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3O5Z
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CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM P85BETA SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE (PI3K)
分子名称:Phosphatidylinositol 3-kinase regulatory subunit beta, CHLORIDE ION, (4S)-2-METHYL-2,4-PENTANEDIOL
著者Chen, S., Xiao, Y., Ponnusamy, R., Tan, J., Lei, J., Hilgenfeld, R.
登録日2010-07-28
公開日2011-08-10
最終更新日2014-09-10
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit
Acta Crystallogr.,Sect.F, 67, 2011
5XJC
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CRYO-EM STRUCTURE OF THE HUMAN SPLICEOSOME JUST PRIOR TO EXON LIGATION AT 3.6 ANGSTROM
分子名称:Pre-mRNA-processing-splicing factor 8, U5 snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
著者Zhang, X., Yan, C., Hang, J., Finci, I.L., Lei, J., Shi, Y.
登録日2017-04-30
公開日2017-07-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
5YLC
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CRYSTAL STRUCTURE OF MCR-1 CATALYTIC DOMAIN
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018