3CZC
 
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5LC0
 
 | Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor | Descriptor: | N-((S)-3-(4-(aminomethyl)phenyl)-1-(((R)-4-guanidino-1-(5-hydroxy-1,3,2-dioxaborinan-2-yl)butyl)amino)-1-oxopropan-2-yl)benzamide, NS2B-NS3 protease,NS2B-NS3 protease | Authors: | Lei, J, Hansen, G, Zhang, L.L, Hilgenfeld, R. | Deposit date: | 2016-06-18 | Release date: | 2016-07-06 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor. Science, 353, 2016
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5HIH
 
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5HOL
 
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4WUR
 
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3BJV
 
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3L8R
 
 | The crystal structure of PtcA from S. mutans | Descriptor: | Putative PTS system, cellobiose-specific IIA component | Authors: | Lei, J, Liu, X, Li, L. | Deposit date: | 2010-01-03 | Release date: | 2010-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of PtcA from Streptococcus mutans To be Published
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4P16
 
 | Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus | Descriptor: | ORF1a, ZINC ION | Authors: | Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R. | Deposit date: | 2014-02-25 | Release date: | 2014-05-07 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features. Antiviral Res., 109C, 2014
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3RK6
 
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6YXJ
 
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8Q18
 
 | The Crystal Structure of Human Carbonic Anhydrase IX in Complex with Sulfonamide | Descriptor: | 1,1,3-tris(oxidanylidene)-2-(2-phenylethyl)-1,2-benzothiazole-6-sulfonamide, Carbonic anhydrase 9, GLYCEROL, ... | Authors: | Leitans, J, Tars, K. | Deposit date: | 2023-07-31 | Release date: | 2023-11-08 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX. Chemmedchem, 18, 2023
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8Q19
 
 | The Crystal Structure of Human Carbonic Anhydrase IX in Complex with Sulfonamide | Descriptor: | 2-but-2-ynyl-1,1,3-tris(oxidanylidene)-1,2-benzothiazole-6-sulfonamide, Carbonic anhydrase 9, GLYCEROL, ... | Authors: | Leitans, J, Tars, K. | Deposit date: | 2023-07-31 | Release date: | 2023-11-08 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX. Chemmedchem, 18, 2023
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8Q1A
 
 | The Crystal Structure of Human Carbonic Anhydrase IX in Complex with inhibitor | Descriptor: | 1,1,3-tris(oxidanylidene)-2-pentyl-1,2-benzothiazole-6-sulfonamide, Carbonic anhydrase 9, GLYCEROL, ... | Authors: | Leitans, J, Tars, K. | Deposit date: | 2023-07-31 | Release date: | 2023-11-08 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX. Chemmedchem, 18, 2023
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5FL4
 
 | Three dimensional structure of human carbonic anhydrase IX in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide | Descriptor: | 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide, ACETIC ACID, CARBONIC ANHYDRASE 9, ... | Authors: | Leitans, J, Tars, K, Zalubovskis, R. | Deposit date: | 2015-10-21 | Release date: | 2015-11-11 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | An Efficient Expression and Crystallization System of the Cancer Asociated Carbonic Anhydrase Isoform Ix. J.Med.Chem., 58, 2015
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5FL6
 
 | Three dimensional structure of human carbonic anhydrase IX in complex with 5-(1-(4-Methylphenyl)-1H-1,2,3-triazol-4-yl)thiophene-2- sulfonamide | Descriptor: | 5-[1-(4-methylphenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide, ACETIC ACID, CARBONIC ANHYDRASE IX, ... | Authors: | Leitans, J, Tars, K, Zalubovskis, R. | Deposit date: | 2015-10-21 | Release date: | 2015-11-11 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | An Efficient Expression and Crystallization System of the Cancer Asociated Carbonic Anhydrase Isoform Ix. J.Med.Chem., 58, 2015
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5FL5
 
 | Three dimensional structure of human carbonic anhydrase IX in complex with 5-(1-(4-Methoxyphenyl)-1H-1,2,3-triazol-4-yl)thiophene-2- sulfonamide | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[1-(4-methoxyphenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide, CARBONIC ANHYDRASE IX, ... | Authors: | Leitans, J, Tars, K, Zalubovskis, R. | Deposit date: | 2015-10-21 | Release date: | 2015-11-11 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | An Efficient Expression and Crystallization System of the Cancer Asociated Carbonic Anhydrase Isoform Ix. J.Med.Chem., 58, 2015
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1F3R
 
 | COMPLEX BETWEEN FV ANTIBODY FRAGMENT AND AN ANALOGUE OF THE MAIN IMMUNOGENIC REGION OF THE ACETYLCHOLINE RECEPTOR | Descriptor: | ACETYLCHOLINE RECEPTOR ALPHA, FV ANTIBODY FRAGMENT | Authors: | Kleinjung, J, Petit, M.-C, Orlewski, P, Mamalaki, A, Tzartos, S.-J, Tsikaris, V, Sakarellos-Daitsiotis, M, Sakarellos, C, Marraud, M, Cung, M.-T. | Deposit date: | 2000-06-06 | Release date: | 2000-06-15 | Last modified: | 2024-10-30 | Method: | SOLUTION NMR | Cite: | The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach. Biopolymers, 53, 2000
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3F7J
 
 | B.subtilis YvgN | Descriptor: | NITRATE ION, POTASSIUM ION, YvgN protein | Authors: | Zhou, Y.F, Lei, J, Liang, Y.H, Su, X.-D. | Deposit date: | 2008-11-09 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis Protein Sci., 18, 2009
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3D3F
 
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5NGN
 
 | Lybatide 2, a cystine-rich peptide from Lycium barbarum | Descriptor: | ACETONITRILE, GLYCEROL, TETRAETHYLENE GLYCOL, ... | Authors: | Lei, J, Tan, W.L, Sakai, N, Hilgenfeld, R. | Deposit date: | 2017-03-18 | Release date: | 2017-07-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold. Sci Rep, 7, 2017
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6TL6
 
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6TL5
 
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9FLF
 
 | Three-Dimensional Structure of Human Carbonic Anhydrase IX in Complex with a Covalent Inhibitor | Descriptor: | 3-[[(1~{R},4~{Z})-cyclododec-4-en-1-yl]amino]-4-ethylsulfonyl-2,5,6-tris(fluoranyl)benzenesulfonamide, Carbonic anhydrase, ZINC ION | Authors: | Leitans, J, Tars, K. | Deposit date: | 2024-06-05 | Release date: | 2024-12-18 | Last modified: | 2025-01-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX. Elife, 13, 2024
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8OO8
 
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7POM
 
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