5FL4

Three dimensional structure of human carbonic anhydrase IX in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide

Summary for 5FL4

Entry DOI	10.2210/pdb5fl4/pdb
Related	5FL5 5FL6
Descriptor	CARBONIC ANHYDRASE 9, ZINC ION, 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide, ... (6 entities in total)
Functional Keywords	lyase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	115106.75
Authors	Leitans, J.,Tars, K.,Zalubovskis, R. (deposition date: 2015-10-21, release date: 2015-11-11, Last modification date: 2024-01-10)
Primary citation	Leitans, J.,Kazaks, A.,Balode, A.,Ivanova, J.,Zalubovskis, R.,Supuran, C.T.,Tars, K. An Efficient Expression and Crystallization System of the Cancer Asociated Carbonic Anhydrase Isoform Ix. J.Med.Chem., 58:9004-, 2015 Cited by PubMed: 26522624 DOI: 10.1021/ACS.JMEDCHEM.5B01343 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation