2JES
 
 | | Portal protein (gp6) from bacteriophage SPP1 | | Descriptor: | CALCIUM ION, MERCURY (II) ION, PORTAL PROTEIN, ... | | Authors: | Lebedev, A.A, Krause, M.H, Isidro, A.L, Vagin, A.A, Orlova, E.V, Turner, J, Dodson, E.J, Tavares, P, Antson, A.A. | | Deposit date: | 2007-01-21 | | Release date: | 2007-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural Framework for DNA Translocation Via the Viral Portal Protein
Embo J., 26, 2007
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2C20
 | | CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GLUCOSE 4-EPIMERASE, ZINC ION | | Authors: | Lebedev, A.A, Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S. | | Deposit date: | 2005-09-22 | | Release date: | 2007-02-20 | | Last modified: | 2025-10-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of Udp-Glucose 4-Epimerase from Bacillus Anthracis at 2.7A Resolution
To be Published
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8Z7K
 | | Crystal structure of Hemolysin co-regulated protein 1 (Hcp1) VariantB from Burkholderia pseudomallei | | Descriptor: | Hcp family type VI secretion system effector, SULFATE ION | | Authors: | Lebedev, A.A, Charoenwattanasatien, R, Tandhavanant, S, Chantratita, N. | | Deposit date: | 2024-04-20 | | Release date: | 2024-12-25 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (1.582 Å) | | Cite: | Genetic variation of hemolysin co-regulated protein 1 affects the immunogenicity and pathogenicity of Burkholderia pseudomallei.
Plos Negl Trop Dis, 19, 2025
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4BQ0
 | | Pseudomonas aeruginosa beta-alanine:pyruvate aminotransferase holoenzyme without divalent cations on dimer-dimer interface | | Descriptor: | BETA-ALANINE--PYRUVATE TRANSAMINASE, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Isupov, M.N, Lebedev, A.A, Westlake, A, Sayer, C, Littlechild, J.A. | | Deposit date: | 2013-05-29 | | Release date: | 2013-06-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Space-Group and Origin Ambiguity in Macromolecular Structures with Pseudo-Symmetry and its Treatment with the Program Zanuda.
Acta Crystallogr.,Sect.D, 70, 2014
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1AX4
 | | TRYPTOPHANASE FROM PROTEUS VULGARIS | | Descriptor: | POTASSIUM ION, TRYPTOPHANASE | | Authors: | Isupov, M.N, Antson, A.A, Dodson, E.J, Dodson, G.G, Dementieva, I.S, Zakomirdina, L.N, Wilson, K.S, Dauter, Z, Lebedev, A.A, Harutyunyan, E.H. | | Deposit date: | 1997-10-28 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of tryptophanase.
J.Mol.Biol., 276, 1998
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5NPT
 | | Structure of the N-terminal domain of the yeast telomerase reverse transcriptase | | Descriptor: | Telomerase reverse transcriptase | | Authors: | Rodina, E.V, Lebedev, A.A, Hakanpaa, J, Hackenberg, C, Petrova, O.A, Zvereva, M.I, Dontsova, O.A, Lamzin, V.S. | | Deposit date: | 2017-04-18 | | Release date: | 2017-12-20 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
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6I7S
 | | Microsomal triglyceride transfer protein | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | Authors: | Biterova, E, Isupov, M.N, Keegan, R.M, Lebedev, A.A, Ruddock, L.W. | | Deposit date: | 2018-11-17 | | Release date: | 2019-08-21 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of human microsomal triglyceride transfer protein.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2YHF
 | | 1.9 Angstrom Crystal Structure of CLEC5A | | Descriptor: | C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A | | Authors: | Watson, A.A, Lebedev, A.A, Murshudov, G.M, Vagin, A.A, Hall, B.A, O'Callaghan, C.A. | | Deposit date: | 2011-04-30 | | Release date: | 2011-05-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Flexibility of the Macrophage Dengue Virus Receptor Clec5A: Implications for Ligand Binding and Signaling.
J.Biol.Chem., 286, 2011
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2W11
 | | Structure of the L-2-haloacid dehalogenase from Sulfolobus tokodaii | | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, 2-HALOALKANOIC ACID DEHALOGENASE | | Authors: | Rye, C.A, Isupov, M.N, Lebedev, A.A, Littlechild, J.A. | | Deposit date: | 2008-10-13 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Biochemical and Structural Studies of a L-Haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii.
Extremophiles, 13, 2009
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2WNY
 | | Structure of Mth689, a DUF54 protein from Methanothermobacter thermautotrophicus | | Descriptor: | CHLORIDE ION, CONSERVED PROTEIN MTH689, NICKEL (II) ION | | Authors: | Ng, C.L, Waterman, D.G, Lebedev, A.A, Smits, C, Ortiz-Lombardia, M, Antson, A.A. | | Deposit date: | 2009-07-21 | | Release date: | 2010-09-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of Mth689, a Duf54 Protein from Methanothermobacter Thermautotrophicus
To be Published
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2V9P
 | | Crystal structure of papillomavirus E1 hexameric helicase DNA-free form | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | | Authors: | Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A. | | Deposit date: | 2007-08-24 | | Release date: | 2007-10-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors.
Nucleic Acids Res., 35, 2007
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2WBM
 | | Crystal structure of mthSBDS, the homologue of the Shwachman-Bodian- Diamond syndrome protein in the euriarchaeon Methanothermobacter thermautotrophicus | | Descriptor: | CHLORIDE ION, GLYCEROL, RIBOSOME MATURATION PROTEIN SDO1 HOMOLOG, ... | | Authors: | Ng, C.L, Isupov, M.N, Lebedev, A.A, Ortiz-Lombardia, M, Antson, A.A. | | Deposit date: | 2009-03-02 | | Release date: | 2009-06-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Conformational Flexibility and Molecular Interactions of an Archaeal Homologue of the Shwachman-Bodian-Diamond Syndrome Protein.
Bmc Struct.Biol., 9, 2009
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7NIT
 | | X-ray structure of a multidomain BbgIII from Bifidobacterium bifidum | | Descriptor: | Beta-galactosidase, CALCIUM ION, GLYCEROL, ... | | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Sanchez Rodriguez, F, Rigden, D.J, Tams, J.W, Wilting, R, Vester, J.K, Longhin, E, Krogh, K.B.R, Pache, R.A, Davies, G.J, Wilson, K.S. | | Deposit date: | 2021-02-14 | | Release date: | 2021-12-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Multitasking in the gut: the X-ray structure of the multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions.
Acta Crystallogr D Struct Biol, 77, 2021
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6H78
 | | E1 enzyme for ubiquitin like protein activation. | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Soudah, N, Padala, P, Hassouna, F, Mashahreh, B, Lebedev, A.A, Isupov, M.N, Cohen-Kfir, E, Wiener, R. | | Deposit date: | 2018-07-30 | | Release date: | 2018-10-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation.
J.Mol.Biol., 431, 2019
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6H77
 | | E1 enzyme for ubiquitin like protein activation in complex with UBL | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Soudah, N, Padala, P, Hassouna, F, Mashahreh, B, Lebedev, A.A, Isupov, M.N, Cohen-Kfir, E, Wiener, R. | | Deposit date: | 2018-07-30 | | Release date: | 2018-10-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation.
J.Mol.Biol., 431, 2019
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5FYP
 | | Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 2 | | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, PHOSPHOINOSITOL-SPECIFIC PHOSPHOLIPASE C, ... | | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Norgaard, A, Segura, D.R, Blicher, T.H, Wilson, K.S. | | Deposit date: | 2016-03-09 | | Release date: | 2017-01-18 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.
Acta Crystallogr D Struct Biol, 73, 2017
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5FYR
 | | Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, myoinositol complex | | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CALCIUM ION, PHOSPHATE ION, ... | | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Norgaard, A, Segura, D.R, Blicher, T.H, Wilson, K.S. | | Deposit date: | 2016-03-09 | | Release date: | 2017-01-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.
Acta Crystallogr D Struct Biol, 73, 2017
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5FYO
 | | Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PHOSPHOINOSITOL-SPECIFIC PHOSPHOLIPASE C | | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Norgaard, A, Segura, D.R, Blicher, T.H, Wilson, K.S. | | Deposit date: | 2016-03-08 | | Release date: | 2017-01-18 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.
Acta Crystallogr D Struct Biol, 73, 2017
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2W43
 | | Structure of L-haloacid dehalogenase from S. tokodaii | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HYPOTHETICAL 2-HALOALKANOIC ACID DEHALOGENASE, PHOSPHATE ION | | Authors: | Rye, C.A, Isupov, M.N, Lebedev, A.A, Littlechild, J.A. | | Deposit date: | 2008-11-21 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Biochemical and Structural Studies of a L-Haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii.
Extremophiles, 13, 2009
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2FX0
 | | Crystal Structure of HlyIIR, a Hemolysin II transcriptional Regulator | | Descriptor: | hemolysin II regulatory protein | | Authors: | Kovalevskiy, O.V, Lebedev, A.A, Solonin, A.S, Antson, A.A. | | Deposit date: | 2006-02-03 | | Release date: | 2006-02-21 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Bacillus cereus HlyIIR, a Transcriptional Regulator of the Gene for Pore-forming Toxin Hemolysin II.
J.Mol.Biol., 365, 2007
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1QMV
 | | thioredoxin peroxidase B from red blood cells | | Descriptor: | PEROXIREDOXIN-2 | | Authors: | Isupov, M.N, Littlechild, J.A, Lebedev, A.A, Errington, N, Vagin, A.A, Schroder, E. | | Deposit date: | 1999-10-07 | | Release date: | 2000-07-28 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of Decameric 2-Cys Peroxiredoxin from Human Erythrocytes at 1.7 A Resolution.
Structure, 8, 2000
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3SS9
 | | Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.97 A resolution | | Descriptor: | D-serine dehydratase, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. | | Deposit date: | 2011-07-08 | | Release date: | 2012-01-18 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
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3SS7
 | | Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.55 A resolution | | Descriptor: | D-serine dehydratase, GLYCEROL, POTASSIUM ION, ... | | Authors: | Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D. | | Deposit date: | 2011-07-07 | | Release date: | 2012-01-18 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
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1GOY
 | | HYDROLASE(ENDORIBONUCLEASE)RIBONUCLEASE BI(G SPECIFIC ENDONUCLEASE) (E.C.3.1.27.-) COMPLEXED WITH GUANOSINE-3'-PHOSPHATE (3'-GMP) | | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE, SULFATE ION | | Authors: | Polyakov, K.M, Lebedev, A.A, Pavlovsky, A.G, Sanishvili, R.G, Dodson, G.G. | | Deposit date: | 2001-10-26 | | Release date: | 2001-11-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Structure of Substrate-Free Microbial Ribonuclease Binase and of its Complexes with 3'Gmp and Sulfate Ions
Acta Crystallogr.,Sect.D, 58, 2002
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1GOV
 | | RIBONUCLEASE BI(G SPECIFIC ENDONUCLEASE) COMPLEXED WITH SULFATE IONS | | Descriptor: | RIBONUCLEASE, SULFATE ION | | Authors: | Polyakov, K.M, Lebedev, A.A, Pavlovsky, A.G, Sanishvili, R.G, Dodson, G.G. | | Deposit date: | 2001-10-26 | | Release date: | 2001-11-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Structure of Substrate-Free Microbial Ribonuclease Binase and of its Complexes with 3'Gmp and Sulfate Ions
Acta Crystallogr.,Sect.D, 58, 2002
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