Author results

6MHS
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN A PUTATIVE SENSITIZED CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHV
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHW
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (1)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHX
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (2)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
3J6E
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ENERGY MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY GMPCPP
Descriptor:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
Deposit date:2014-02-18
Release date:2014-06-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6F
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MINIMIZED AVERAGE STRUCTURE OF GDP-BOUND DYNAMIC MICROTUBULES
Descriptor:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
Deposit date:2014-02-19
Release date:2014-06-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6G
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MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY TAXOL
Descriptor:Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E.
Deposit date:2014-02-19
Release date:2014-06-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3JCK
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STRUCTURE OF THE YEAST 26S PROTEASOME LID SUB-COMPLEX
Descriptor:26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit RPN6, ...
Authors:Herzik Jr., M.A., Dambacher, C.M., Worden, E.J., Martin, A., Lander, G.C.
Deposit date:2015-12-20
Release date:2016-01-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.
Elife, 5, 2016
4YLR
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TUBULIN GLUTAMYLASE
Descriptor:Tubulin polyglutamylase TTLL7, ADENOSINE-5'-DIPHOSPHATE
Authors:Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
4YLS
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TUBULIN GLUTAMYLASE
Descriptor:Tubulin polyglutamylase TTLL7, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
5AN8
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RABBIT TRPV2 ION CHANNEL
Descriptor:TRPV2
Authors:Zubcevic, L., Herzik, M.A.J., Chung, B.C., Lander, G.C., Lee, S.Y.
Deposit date:2015-09-04
Release date:2015-12-23
Last modified:2016-03-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-Electron Microscopy of the Trpv2 Ion Channel
Nat.Struct.Mol.Biol., 23, 2016
5UZ9
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CRYO EM STRUCTURE OF ANTI-CRISPRS, ACRF1 AND ACRF2, BOUND TO TYPE I-F CRRNA-GUIDED CRISPR SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Chowdhury, S., Carter, J., Rollins, M.F., Jackson, R.N., Hoffmann, C., Nosaka, L., Bondy-Denomy, J., Maxwell, K.L., Davidson, A.R., Fischer, E.R., Lander, G.C., Wiedenheft, B.
Deposit date:2017-02-25
Release date:2017-04-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.
Cell, 169, 2017
5VY3
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THERMOPLASMA ACIDOPHILUM 20S PROTEASOME USING 200KEV WITH STAGE POSITION
Descriptor:Proteasome subunit alpha, Proteasome subunit beta
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2017-05-24
Release date:2017-06-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Achieving better-than-3- angstrom resolution by single-particle cryo-EM at 200 keV.
Nat. Methods, 14, 2017
5VY4
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THERMOPLASMA ACIDOPHILUM 20S PROTEASOME USING 200KEV WITH IMAGE SHIFT
Descriptor:Proteasome subunit alpha, Proteasome subunit beta
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2017-05-24
Release date:2017-06-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Achieving better-than-3- angstrom resolution by single-particle cryo-EM at 200 keV.
Nat. Methods, 14, 2017
5VY5
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RABBIT MUSCLE ALDOLASE USING 200KEV
Descriptor:Fructose-bisphosphate aldolase A
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2017-05-24
Release date:2017-06-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Achieving better-than-3- angstrom resolution by single-particle cryo-EM at 200 keV.
Nat. Methods, 14, 2017
5W3S
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF A TRPML3 ION CHANNEL
Descriptor:Mucolipin-3 isoform 1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
Authors:Hirschi, M., Herzik, M.A., Wie, J., Suo, Y., Borschel, W.F., Ren, D., Lander, G.C., Lee, S.Y.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2017-11-01
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Nature, 550, 2017
6AZ0
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MITOCHONDRIAL ATPASE PROTEASE YME1
Descriptor:Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1, poly(UNK), ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Puchades, C., Rampello, A.J., Shin, M., Giuliano, C., Wiseman, R.L., Glynn, S.E., Lander, G.C.
Deposit date:2017-09-09
Release date:2017-11-15
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.
Science, 358, 2017
6BPQ
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STRUCTURE OF THE COLD- AND MENTHOL-SENSING ION CHANNEL TRPM8
Descriptor:Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y., Wu, M., Zubcevic, L., Borschel, W.F., Lander, G.C., Lee, S.-Y.
Deposit date:2017-11-25
Release date:2017-12-13
Last modified:2018-01-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the cold- and menthol-sensing ion channel TRPM8.
Science, 359, 2018
6DT0
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CRYO-EM STRUCTURE OF A MITOCHONDRIAL CALCIUM UNIPORTER
Descriptor:Mitochondrial calcium uniporter, CALCIUM ION
Authors:Yoo, J., Wu, M., Yin, Y., Herzik, M.A.J., Lander, G.C., Lee, S.-Y.
Deposit date:2018-06-14
Release date:2018-07-11
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of a mitochondrial calcium uniporter.
Science, 361, 2018
6EF0
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YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (1D* MOTOR STATE)
Descriptor:Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 2018
6EF1
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YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (5D MOTOR STATE)
Descriptor:Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.73 Å)
Cite:Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 2018
6EF2
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YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (5T MOTOR STATE)
Descriptor:Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 2018
6EF3
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YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (4D MOTOR STATE)
Descriptor:Proteasome subunit beta type-1, Proteasome subunit beta type-2, Proteasome subunit beta type-3, ...
Authors:de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 2018
6MHO
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN THE APO CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MPU
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STRUCTURE OF DOUBLE-STRANDED TARGET DNA ENGAGED CSY COMPLEX FROM PSEUDOMONAS AERUGINOSA (PA-14)
Descriptor:CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, CRISPR-associated endonuclease Cas6/Csy4, ...
Authors:Chowdhury, S., Rollins, M.F., Carter, J., Golden, S.M., Miettinen, H.M., Santiago-Frangos, A., Faith, D., Lawrence, M.C., Wiedenheft, B., Lander, G.C.
Deposit date:2018-10-08
Release date:2018-10-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14)
To be Published
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