6NYY | | HUMAN M-AAA PROTEASE AFG3L2, SUBSTRATE-BOUND | | Descriptor: | AFG3-like protein 2, Substrate, ZINC ION, ... | | Authors: | Lander, G.C., Puchades, C. | | Deposit date: | 2019-02-12 | | Release date: | 2019-05-22 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.
Mol.Cell, 75, 2019
|
|
6MHS | | STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN A PUTATIVE SENSITIZED CONFORMATION | | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | | Authors: | Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y. | | Deposit date: | 2018-09-18 | | Release date: | 2018-10-03 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
|
|
6MHV | | STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C4 SYMMETRY | | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | | Authors: | Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y. | | Deposit date: | 2018-09-18 | | Release date: | 2018-10-03 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
|
|
6MHW | | STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (1) | | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | | Authors: | Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y. | | Deposit date: | 2018-09-18 | | Release date: | 2018-10-03 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
|
|
6MHX | | STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (2) | | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | | Authors: | Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y. | | Deposit date: | 2018-09-18 | | Release date: | 2018-10-03 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
|
|
3J6E | | ENERGY MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY GMPCPP | | Descriptor: | Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E. | | Deposit date: | 2014-02-18 | | Release date: | 2014-06-04 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
|
|
3J6F | | MINIMIZED AVERAGE STRUCTURE OF GDP-BOUND DYNAMIC MICROTUBULES | | Descriptor: | Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E. | | Deposit date: | 2014-02-19 | | Release date: | 2014-06-04 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
|
|
3J6G | | MINIMIZED AVERAGE STRUCTURE OF MICROTUBULES STABILIZED BY TAXOL | | Descriptor: | Tubulin alpha-1A chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Alushin, G.M., Lander, G.C., Kellogg, E.H., Zhang, R., Baker, D., Nogales, E. | | Deposit date: | 2014-02-19 | | Release date: | 2014-06-04 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
|
|
3JCK | | STRUCTURE OF THE YEAST 26S PROTEASOME LID SUB-COMPLEX | | Descriptor: | 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit RPN6, ... | | Authors: | Herzik Jr., M.A., Dambacher, C.M., Worden, E.J., Martin, A., Lander, G.C. | | Deposit date: | 2015-12-20 | | Release date: | 2016-01-20 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.
Elife, 5, 2016
|
|
4YLR | | TUBULIN GLUTAMYLASE | | Descriptor: | Tubulin polyglutamylase TTLL7, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A. | | Deposit date: | 2015-03-05 | | Release date: | 2015-06-17 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
|
|
4YLS | | TUBULIN GLUTAMYLASE | | Descriptor: | Tubulin polyglutamylase TTLL7, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Garnham, C.P., Vemu, A., Wilson-Kubalek, E.M., Yu, I., Szyk, A., Lander, G.C., Milligan, R.A., Roll-Mecak, A. | | Deposit date: | 2015-03-05 | | Release date: | 2015-06-17 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
|
|
5AN8 | | CRYO-ELECTRON MICROSCOPY STRUCTURE OF RABBIT TRPV2 ION CHANNEL | | Descriptor: | TRPV2 | | Authors: | Zubcevic, L., Herzik, M.A.J., Chung, B.C., Lander, G.C., Lee, S.Y. | | Deposit date: | 2015-09-04 | | Release date: | 2015-12-23 | | Last modified: | 2019-04-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-Electron Microscopy of the Trpv2 Ion Channel
Nat.Struct.Mol.Biol., 23, 2016
|
|
5UZ9 | | CRYO EM STRUCTURE OF ANTI-CRISPRS, ACRF1 AND ACRF2, BOUND TO TYPE I-F CRRNA-GUIDED CRISPR SURVEILLANCE COMPLEX | | Descriptor: | CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ... | | Authors: | Chowdhury, S., Carter, J., Rollins, M.F., Jackson, R.N., Hoffmann, C., Nosaka, L., Bondy-Denomy, J., Maxwell, K.L., Davidson, A.R., Fischer, E.R., Lander, G.C., Wiedenheft, B. | | Deposit date: | 2017-02-25 | | Release date: | 2017-04-26 | | Last modified: | 2019-11-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.
Cell, 169, 2017
|
|
5VY3 | |
5VY4 | |
5VY5 | | RABBIT MUSCLE ALDOLASE USING 200KEV | | Descriptor: | Fructose-bisphosphate aldolase A | | Authors: | Herzik Jr., M.A., Wu, M., Lander, G.C. | | Deposit date: | 2017-05-24 | | Release date: | 2017-06-14 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Achieving better-than-3- angstrom resolution by single-particle cryo-EM at 200 keV.
Nat. Methods, 14, 2017
|
|
5W3S | | CRYO-ELECTRON MICROSCOPY STRUCTURE OF A TRPML3 ION CHANNEL | | Descriptor: | Mucolipin-3 isoform 1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | | Authors: | Hirschi, M., Herzik, M.A., Wie, J., Suo, Y., Borschel, W.F., Ren, D., Lander, G.C., Lee, S.Y. | | Deposit date: | 2017-06-08 | | Release date: | 2017-10-11 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Nature, 550, 2017
|
|
6AZ0 | | MITOCHONDRIAL ATPASE PROTEASE YME1 | | Descriptor: | Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1, poly(UNK), ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Puchades, C., Rampello, A.J., Shin, M., Giuliano, C., Wiseman, R.L., Glynn, S.E., Lander, G.C. | | Deposit date: | 2017-09-09 | | Release date: | 2017-11-15 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.
Science, 358, 2017
|
|
6BPQ | | STRUCTURE OF THE COLD- AND MENTHOL-SENSING ION CHANNEL TRPM8 | | Descriptor: | Transient receptor potential cation channel subfamily M member 8 | | Authors: | Yin, Y., Wu, M., Zubcevic, L., Borschel, W.F., Lander, G.C., Lee, S.-Y. | | Deposit date: | 2017-11-25 | | Release date: | 2017-12-13 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the cold- and menthol-sensing ion channel TRPM8.
Science, 359, 2018
|
|
6D73 | | CRYO-EM STRUCTURE OF THE ZEBRAFISH TRPM2 CHANNEL IN THE PRESENCE OF CA2+ | | Descriptor: | Transient receptor potential cation channel, subfamily M, CALCIUM ION | | Authors: | Yin, Y., Wu, M., Borschel, W.F., Lander, G.C., Lee, S.-Y. | | Deposit date: | 2018-04-23 | | Release date: | 2019-05-15 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Nat Commun, 10, 2019
|
|
6DT0 | | CRYO-EM STRUCTURE OF A MITOCHONDRIAL CALCIUM UNIPORTER | | Descriptor: | Mitochondrial calcium uniporter, CALCIUM ION | | Authors: | Yoo, J., Wu, M., Yin, Y., Herzik, M.A.J., Lander, G.C., Lee, S.-Y. | | Deposit date: | 2018-06-14 | | Release date: | 2018-07-11 | | Last modified: | 2018-08-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of a mitochondrial calcium uniporter.
Science, 361, 2018
|
|
6EF0 | | YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (1D* MOTOR STATE) | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.43 Å) | | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
|
|
6EF1 | | YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (5D MOTOR STATE) | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (4.73 Å) | | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
|
|
6EF2 | | YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (5T MOTOR STATE) | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (4.27 Å) | | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
|
|
6EF3 | | YEAST 26S PROTEASOME BOUND TO UBIQUITINATED SUBSTRATE (4D MOTOR STATE) | | Descriptor: | Proteasome subunit beta type-1, Proteasome subunit beta type-2, Proteasome subunit beta type-3, ... | | Authors: | de la Pena, A.H., Goodall, E.A., Gates, S.N., Lander, G.C., Martin, A. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
|
|
