8JHK
| Cryo-EM structure of the DOCK5/ELMO1 complex, focused on one protomer | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2023-05-23 | Release date: | 2024-05-29 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.76 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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1UDX
| Crystal structure of the conserved protein TT1381 from Thermus thermophilus HB8 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, the GTP-binding protein Obg | Authors: | Kukimoto-Niino, M, Shirouzu, M, Murayama, K, Inoue, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-07 | Release date: | 2004-03-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8. J.Mol.Biol., 337, 2004
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8I5W
| Crystal structure of the DHR-2 domain of DOCK10 in complex with Rac1 | Descriptor: | Dedicator of cytokinesis protein 10, Ras-related C3 botulinum toxin substrate 1, SULFATE ION | Authors: | Kukimoto-Niino, M, Mishima-Tsumagari, C, Ihara, K, Fukui, Y, Yokoyama, S, Shirouzu, M. | Deposit date: | 2023-01-26 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.432 Å) | Cite: | Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor. Biochem.Biophys.Res.Commun., 653, 2023
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8I5F
| Crystal structure of the DHR-2 domain of DOCK10 in complex with Cdc42 (T17N mutant) | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10 | Authors: | Kukimoto-Niino, M, Mishima-Tsumagari, C, Fukui, Y, Yokoyama, S, Shirouzu, M. | Deposit date: | 2023-01-25 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor. Biochem.Biophys.Res.Commun., 653, 2023
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8I5V
| DOCK10 mutant L1903Y complexed with Rac1 | Descriptor: | Dedicator of cytokinesis protein 10, Ras-related C3 botulinum toxin substrate 1, SULFATE ION | Authors: | Kukimoto-Niino, M, Mishima-Tsumagari, C, Ihara, K, Fukui, Y, Yokoyama, S, Shirouzu, M. | Deposit date: | 2023-01-26 | Release date: | 2023-03-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.726 Å) | Cite: | Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor. Biochem.Biophys.Res.Commun., 653, 2023
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8ZJJ
| Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 2) | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-15 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8ZJL
| Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 4) | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-15 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.31 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8ZJ2
| Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-14 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8ZJK
| Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 3) | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-15 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8ZJM
| Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 5) | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-15 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.52 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8ZJI
| Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 1) | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-15 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8XM7
| Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2023-12-27 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.91 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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7DPA
| Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Kukimoto-Niino, M, Katsura, K, Kaushik, R, Ehara, H, Yokoyama, T, Uchikubo-Kamo, T, Mishima-Tsumagari, C, Yonemochi, M, Ikeda, M, Hanada, K, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2020-12-18 | Release date: | 2021-08-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex. Sci Adv, 7, 2021
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6AJ4
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6AJL
| DOCK7 mutant I1836Y complexed with Cdc42 | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 | Authors: | Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
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1WEH
| Crystal structure of the conserved hypothetical protein TT1887 from Thermus thermophilus HB8 | Descriptor: | Conserved hypothetical protein TT1887 | Authors: | Kukimoto-Niino, M, Murayama, K, Idaka, M, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-25 | Release date: | 2004-11-25 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8 PROTEIN SCI., 13, 2004
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1WEK
| Crystal structure of the conserved hypothetical protein TT1465 from Thermus thermophilus HB8 | Descriptor: | PHOSPHATE ION, hypothetical protein TT1465 | Authors: | Kukimoto-Niino, M, Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-25 | Release date: | 2004-11-25 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8 Protein Sci., 13, 2004
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1X3S
| Crystal structure of human Rab18 in complex with Gppnhp | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-18 | Authors: | Kukimoto-Niino, M, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-10 | Release date: | 2005-11-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Crystal structure of human Rab18 in complex with Gppnhp To be Published
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2ZET
| Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Melanophilin, ... | Authors: | Kukimoto-Niino, M, Sakamoto, A, Kanno, E, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Fukuda, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-12-17 | Release date: | 2008-09-30 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure, 16, 2008
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2EG9
| Crystal structure of the truncated extracellular domain of mouse CD38 | Descriptor: | ADP-ribosyl cyclase 1 | Authors: | Kukimoto-Niino, M, Mishima, C, Wakiyama, M, Terada, T, Shirouzu, M, Hara-Yokoyama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-28 | Release date: | 2008-03-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the truncated extracellular domain of mouse CD38 To be Published
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2DWG
| RUN domain of Rap2 interacting protein x, crystallized in P2(1)2(1)2(1) space group | Descriptor: | Protein RUFY3 | Authors: | Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-11 | Release date: | 2006-10-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
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2E87
| Crystal structure of hypothetical GTP-binding protein PH1320 from Pyrococcus horikoshii OT3, in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Hypothetical protein PH1320, SULFATE ION | Authors: | Kukimoto-Niino, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-19 | Release date: | 2007-07-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of hypothetical GTP-binding protein PH1320 from Pyrococcus horikoshii OT3, in complex with GDP To be Published
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2E0A
| Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyruvate dehydrogenase kinase isozyme 4 | Authors: | Kukimoto-Niino, M, Tokmakov, A, Terada, T, Shiromizu, I, Kawamoto, M, Matsusue, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-10-03 | Release date: | 2007-10-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4. Acta Crystallogr.,Sect.D, 67, 2011
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2EF1
| Crystal structure of the extracellular domain of human CD38 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADP-ribosyl cyclase 1 | Authors: | Kukimoto-Niino, M, Nureki, O, Murayama, K, Shirouzu, M, Katada, T, Hara-Yokoyama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-20 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the extracellular domain of human CD38 To be Published
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2CXL
| RUN domain of Rap2 interacting protein x, crystallized in I422 space group | Descriptor: | rap2 interacting protein x | Authors: | Kukimoto-Niino, M, Umehara, T, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-30 | Release date: | 2005-12-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
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