Author results

6IQ5
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CRYSTAL STRUCTURE OF CYP1B1 AND INHIBITOR HAVING AZIDE GROUP
Descriptor:Cytochrome P450 1B1, PROTOPORPHYRIN IX CONTAINING FE, 2-(cis-4-azidocyclohexyl)-4H-naphtho[1,2-b]pyran-4-one
Authors:Kubo, M., Yamamoto, K., Itoh, T.
Deposit date:2018-11-06
Release date:2019-01-30
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Design and synthesis of selective CYP1B1 inhibitor via dearomatization of alpha-naphthoflavone.
Bioorg. Med. Chem., 27, 2019
5J7A
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BACTERIORHODOPSIN GROUND STATE STRUCTURE OBTAINED WITH SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL
Authors:Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W., Conrad, C., Coe, J., Bean, R., Zhao, Y., Bath, P., Dods, R., Harimoorthy, R., Beyerlein, K.R., Rheinberger, J., James, D., DePonte, D., Li, C., Sala, L., Williams, G., Hunter, M., Koglin, J.E., Berntsen, P., Nango, E., Iwata, S., Chapman, H.N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T.A., Weierstall, U., Spence, J., Neutze, R., Schertler, G., Standfuss, J.
Deposit date:2016-04-06
Release date:2016-08-31
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography.
Nat Commun, 7, 2016
5X19
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CO BOUND CYTOCHROME C OXIDASE AT 100 MICRO SEC AFTER PUMP LASER IRRADIATION TO RELEASE CO FROM O2 REDUCTION CENTER
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
5X1B
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CO BOUND CYTOCHROME C OXIDASE AT 20 NSEC AFTER PUMP LASER IRRADIATION TO RELEASE CO FROM O2 REDUCTION CENTER
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
5X1F
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CO BOUND CYTOCHROME C OXIDASE WITHOUT PUMP LASER IRRADIATION AT 278K
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
5Y5F
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STRUCTURE OF CYTOCHROME P450NOR IN NO-BOUND STATE: DAMAGED BY LOW-DOSE (0.72 MGY) X-RAY
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Ueno, G., Murakami, H., Yamashita, K., Hirata, K., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5G
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STRUCTURE OF CYTOCHROME P450NOR IN NO-BOUND STATE: DAMAGED BY LOW-DOSE (0.72 MGY) X-RAY
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Ueno, G., Murakami, H., Yamashita, K., Hirata, K., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5H
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SF-ROX STRUCTURE OF CYTOCHROME P450NOR (NO-BOUND STATE) DETERMINED AT SACLA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Yamagiwa, R., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Yamashita, A., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5I
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: 20 MS AFTER PHOTO-IRRADIATION OF CAGED NO IN THE PRESENCE OF NADH (NO-BOUND STATE), LIGHT DATA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5J
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: DARK-2 DATA IN THE PRESENCE OF NADH (RESTING STATE)
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5K
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR : 20 MS AFTER PHOTO-IRRADIATION OF CAGED NO IN THE ABSENCE OF NADH (NO-BOUND STATE), LIGHT DATA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5L
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: DARK-2 DATA IN THE ABSENCE OF NADH (RESTING STATE)
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5M
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SFX STRUCTURE OF CYTOCHROME P450NOR: A COMPLETE DARK DATA WITHOUT PUMP LASER (RESTING STATE)
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5B6V
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: RESTING STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Nango, E., Royant, A., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-06-02
Release date:2016-12-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5B6W
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 16 NS AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-06-02
Release date:2016-12-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5B6X
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 760 NS AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-06-02
Release date:2016-12-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5B6Y
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 36.2 US AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-06-02
Release date:2016-12-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5B6Z
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 1.725 MS US AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-06-02
Release date:2016-12-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5GTH
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NATIVE XFEL STRUCTURE OF PHOTOSYSTEM II (DARK DATASET)
Descriptor:Photosystem II protein D1, Photosystem II CP47 reaction center protein, Photosystem II CP43 reaction center protein, ...
Authors:Suga, M., Shen, J.R.
Deposit date:2016-08-20
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
5GTI
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NATIVE XFEL STRUCTURE OF PHOTOSYSTEM II (TWO FLASH DATASET)
Descriptor:Photosystem II D1 protein, Photosystem II CP47 reaction center protein, Photosystem II CP43 protein, ...
Authors:Suga, M., Shen, J.R.
Deposit date:2016-08-20
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
5H2H
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 40 NS AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5H2I
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 110 NS AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5H2J
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 290 NS AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5H2K
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 2 US AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5H2L
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A THREE DIMENSIONAL MOVIE OF STRUCTURAL CHANGES IN BACTERIORHODOPSIN: STRUCTURE OBTAINED 5.25 US AFTER PHOTOEXCITATION
Descriptor:Bacteriorhodopsin, RETINAL, 2,3-DI-PHYTANYL-GLYCEROL, ...
Authors:Royant, A., Nango, E., Nakane, T., Tanaka, T., Arima, T., Neutze, R., Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
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