1EJI | | RECOMBINANT SERINE HYDROXYMETHYLTRANSFERASE (MOUSE) | | Descriptor: | SERINE HYDROXYMETHYLTRANSFERASE, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID | | Authors: | Szebenyi, D.M.E., Liu, X., Kriksunov, I.A., Stover, P.J., Thiel, D.J. | | Deposit date: | 2000-03-02 | | Release date: | 2000-11-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers.
Biochemistry, 39, 2000
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1QWO | | CRYSTAL STRUCTURE OF A PHOSPHORYLATED PHYTASE FROM ASPERGILLUS FUMIGATUS, REVEALING THE STRUCTURAL BASIS FOR ITS HEAT RESILIENCE AND CATALYTIC PATHWAY | | Descriptor: | phytase, N-ACETYL-D-GLUCOSAMINE | | Authors: | Xiang, T., Liu, Q., Deacon, A.M., Koshy, M., Kriksunov, I.A., Lei, X.G., Hao, Q., Thiel, D.J. | | Deposit date: | 2003-09-03 | | Release date: | 2004-06-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of a Heat-resilient Phytase from Aspergillus fumigatus, Carrying a Phosphorylated Histidine
J.Mol.Biol., 339, 2004
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1R0S | | CRYSTAL STRUCTURE OF ADP-RIBOSYL CYCLASE GLU179ALA MUTANT | | Descriptor: | ADP-ribosyl cyclase | | Authors: | Love, M.L., Szebenyi, D.M.E., Kriksunov, I.A., Thiel, D.J., Munshi, C., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2003-09-22 | | Release date: | 2004-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
Structure, 12, 2004
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1R12 | | NATIVE APLYSIA ADP RIBOSYL CYCLASE | | Descriptor: | ADP-ribosyl cyclase | | Authors: | Love, M.L., Szebenyi, D.M.E., Kriksunov, I.A., Thiel, D.J., Munshi, C., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2003-09-23 | | Release date: | 2004-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
Structure, 12, 2004
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1R15 | | APLYSIA ADP RIBOSYL CYCLASE WITH BOUND NICOTINAMIDE AND R5P | | Descriptor: | ADP-ribosyl cyclase, ANY 5'-MONOPHOSPHATE NUCLEOTIDE, NICOTINAMIDE | | Authors: | Love, M.L., Szebenyi, D.M.E., Kriksunov, I.A., Thiel, D.J., Munshi, C., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2003-09-23 | | Release date: | 2004-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
Structure, 12, 2004
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1R16 | | APLYSIA ADP RIBOSYL CYCLASE WITH BOUND PYRIDYLCARBINOL AND R5P | | Descriptor: | ADP-ribosyl cyclase, ANY 5'-MONOPHOSPHATE NUCLEOTIDE, 3-PYRIDINYLCARBINOL | | Authors: | Love, M.L., Szebenyi, D.M.E., Kriksunov, I.A., Thiel, D.J., Munshi, C., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2003-09-23 | | Release date: | 2004-03-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
Structure, 12, 2004
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1TW9 | | GLUTATHIONE TRANSFERASE-2, APO FORM, FROM THE NEMATODE HELIGMOSOMOIDES POLYGYRUS | | Descriptor: | glutathione S-transferase 2 | | Authors: | Schuller, D.J., Liu, Q., Kriksunov, I.A., Campbell, A.M., Barrett, J., Brophy, P.M., Hao, Q. | | Deposit date: | 2004-06-30 | | Release date: | 2004-08-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus.
Proteins, 61, 2005
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1YH3 | | CRYSTAL STRUCTURE OF HUMAN CD38 EXTRACELLULAR DOMAIN | | Descriptor: | ADP-ribosyl cyclase 1 | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Munshi, C., Lee, H.C., Hao, Q. | | Deposit date: | 2005-01-06 | | Release date: | 2005-09-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of human CD38 extracellular domain.
Structure, 13, 2005
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1ZL9 | | CRYSTAL STRUCTURE OF A MAJOR NEMATODE C.ELEGANS SPECIFIC GST (CE01613) | | Descriptor: | glutathione S-transferase 5, GLUTATHIONE | | Authors: | Kriksunov, I.A., Liu, Q., Schuller, D.J., Campbell, A.M., Barrett, J., Brophy, P.M., Hao, Q. | | Deposit date: | 2005-05-05 | | Release date: | 2005-05-17 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal structure of a major nematode C.elegans specific GST (CE01613)
To be Published
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2FNP | | CRYSTAL STRUCTURE OF SARA | | Descriptor: | Staphylococcal accessory regulator A | | Authors: | Liu, Y., Manna, A.C., Pan, C.H., Cheung, A.L., Zhang, G. | | Deposit date: | 2006-01-11 | | Release date: | 2006-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FRH | | CRYSTAL STRUCTURE OF SARA, A TRANSCRIPTION REGULATOR FROM STAPHYLOCOCCUS AUREUS | | Descriptor: | Staphylococcal accessory regulator A, CALCIUM ION | | Authors: | Liu, Y., Manna, A.C., Ingavale, S., Cheung, A.L., Zhang, G. | | Deposit date: | 2006-01-19 | | Release date: | 2006-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HCT | | ACIDIC RESIDUES AT THE ACTIVE SITES OF CD38 AND ADP-RIBOSYL CYCLASE DETERMINE NAAPD SYNTHESIS AND HYDROLYSIS ACTIVITIES | | Descriptor: | ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | | Authors: | Liu, Q., Kriksunov, I.A., Hao, Q., Graeff, R., Lee, H.C. | | Deposit date: | 2006-06-18 | | Release date: | 2006-08-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities.
J.Biol.Chem., 281, 2006
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2I65 | | STRUCTURAL BASIS FOR THE MECHANISTIC UNDERSTANDING HUMAN CD38 CONTROLLED MULTIPLE CATALYSIS | | Descriptor: | ADP-ribosyl cyclase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Munshi, C., Lee, H.C., Hao, Q. | | Deposit date: | 2006-08-28 | | Release date: | 2006-09-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
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2I66 | | STRUCTURAL BASIS FOR THE MECHANISTIC UNDERSTANDING HUMAN CD38 CONTROLLED MULTIPLE CATALYSIS | | Descriptor: | ADP-ribosyl cyclase 1, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4R,5S)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Munshi, C., Lee, H.C., Hao, Q. | | Deposit date: | 2006-08-28 | | Release date: | 2006-09-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
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2I67 | | STRUCTURAL BASIS FOR THE MECHANISTIC UNDERSTANDING HUMAN CD38 CONTROLLED MULTIPLE CATALYSIS | | Descriptor: | ADP-ribosyl cyclase 1, ADENOSINE-5-DIPHOSPHORIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Munshi, C., Lee, H.C., Hao, Q. | | Deposit date: | 2006-08-28 | | Release date: | 2006-09-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
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2O3Q | | STRUCTURAL BASIS FOR FORMATION AND HYDROLYSIS OF CALCIUM MESSENGER CYCLIC ADP-RIBOSE BY HUMAN CD38 | | Descriptor: | ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2006-12-01 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
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2O3R | | STRUCTURAL BASIS FOR FORMATION AND HYDROLYSIS OF CALCIUM MESSENGER CYCLIC ADP-RIBOSE BY HUMAN CD38 | | Descriptor: | ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2006-12-01 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
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2O3S | | STRUCTURAL BASIS FOR FORMATION AND HYDROLYSIS OF CALCIUM MESSENGER CYCLIC ADP-RIBOSE BY HUMAN CD38 | | Descriptor: | ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2006-12-01 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
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2O3T | | STRUCTURAL BASIS FOR FORMATION AND HYDROLYSIS OF CALCIUM MESSENGER CYCLIC ADP-RIBOSE BY HUMAN CD38 | | Descriptor: | ADP-ribosyl cyclase 1, CYCLIC GUANOSINE DIPHOSPHATE-RIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2006-12-01 | | Release date: | 2006-12-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
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2O3U | | STRUCTURAL BASIS FOR FORMATION AND HYDROLYSIS OF CALCIUM MESSENGER CYCLIC ADP-RIBOSE BY HUMAN CD38 | | Descriptor: | ADP-ribosyl cyclase 1, 3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]PYRIDINIUM | | Authors: | Liu, Q., Kriksunov, I.A., Graeff, R., Lee, H.C., Hao, Q. | | Deposit date: | 2006-12-01 | | Release date: | 2006-12-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
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2PGJ | | CATALYSIS ASSOCIATED CONFORMATIONAL CHANGES REVEALED BY HUMAN CD38 COMPLEXED WITH A NON-HYDROLYZABLE SUBSTRATE ANALOG | | Descriptor: | ADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Moreau, C., Graeff, R., Potter, B.V.L., Lee, H.C., Hao, Q. | | Deposit date: | 2007-04-09 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
J.Biol.Chem., 282, 2007
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2PGL | | CATALYSIS ASSOCIATED CONFORMATIONAL CHANGES REVEALED BY HUMAN CD38 COMPLEXED WITH A NON-HYDROLYZABLE SUBSTRATE ANALOG | | Descriptor: | ADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE | | Authors: | Liu, Q., Kriksunov, I.A., Moreau, C., Graeff, R., Potter, B.V.L., Lee, H.C., Hao, Q. | | Deposit date: | 2007-04-09 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
J.Biol.Chem., 282, 2007
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3DZF | | CRYSTAL STRUCTURE OF HUMAN CD38 EXTRACELLULAR DOMAIN COMPLEXED WITH A COVALENT INTERMEDIATE, ARA-F-RIBOSE-5'-PHOSPHATE | | Descriptor: | ADP-ribosyl cyclase 1, 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose | | Authors: | Liu, Q., Kriksunov, I.A., Jiang, H., Graeff, R., Lin, H., Lee, H.C., Hao, Q. | | Deposit date: | 2008-07-29 | | Release date: | 2008-11-04 | | Last modified: | 2016-06-08 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
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3DZG | | CRYSTAL STRUCTURE OF HUMAN CD38 EXTRACELLULAR DOMAIN, ARA-F-RIBOSE-5'-PHOSPHATE/NICOTINAMIDE COMPLEX | | Descriptor: | ADP-ribosyl cyclase 1, 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose, NICOTINAMIDE | | Authors: | Liu, Q., Kriksunov, I.A., Jiang, H., Graeff, R., Lin, H., Lee, H.C., Hao, Q. | | Deposit date: | 2008-07-29 | | Release date: | 2008-11-04 | | Last modified: | 2016-06-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
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3DZH | | CRYSTAL STRUCTURE OF HUMAN CD38 EXTRACELLULAR DOMAIN, GTP COMPLEX | | Descriptor: | ADP-ribosyl cyclase 1, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Liu, Q., Kriksunov, I.A., Jiang, H., Graeff, R., Lin, H., Lee, H.C., Hao, Q. | | Deposit date: | 2008-07-29 | | Release date: | 2008-11-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
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