Aplysia ADP ribosyl cyclase with bound nicotinamide and R5P

Summary for 1R15

Related1R0S 1R12 1R16 1LBE 1ISM 1ISJ 1ISI 1ISH 1ISG
DescriptorADP-ribosyl cyclase, ANY 5'-MONOPHOSPHATE NUCLEOTIDE, NICOTINAMIDE (3 entities in total)
Functional Keywordsadp-ribosyl cyclase, cyclic adp-ribose, naadp, ca2+ signalling, hydrolase
Biological sourceAplysia californica (California sea hare)
Cellular locationCytoplasmic vesicle P29241
Total number of polymer chains8
Total molecular weight240306.44
Love, M.L.,Szebenyi, D.M.E.,Kriksunov, I.A.,Thiel, D.J.,Munshi, C.,Graeff, R.,Lee, H.C.,Hao, Q. (deposition date: 2003-09-23, release date: 2004-03-09, Last modification date: 2011-07-13)
Primary citation
Love, M.L.,Szebenyi, D.M.,Kriksunov, I.A.,Thiel, D.J.,Munshi, C.,Graeff, R.,Lee, H.C.,Hao, Q.
ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
Structure, 12:477-486, 2004
PubMed: 15016363 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2004.02.006
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27018 0.5% 4.8% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16