Author results

3H1Z
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MOLECULAR BASIS FOR THE ASSOCIATION OF PIPKIGAMMA -P90 WITH THE CLATHRIN ADAPTOR AP-2
Descriptor:AP-2 complex subunit beta-1, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
Authors:Vahedi-Faridi, A., Kahlfeldt, N., Schaefer, J.G., Krainer, G., Keller, S., Saenger, W., Krauss, M., Haucke, V.
Deposit date:2009-04-14
Release date:2009-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
J.Biol.Chem., 285, 2010
3RWP
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DISCOVERY OF A NOVEL, POTENT AND SELECTIVE INHIBITOR OF 3-PHOSPHOINOSITIDE DEPENDENT KINASE (PDK1)
Descriptor:3-phosphoinositide-dependent protein kinase 1, GLYCEROL, SULFATE ION, ...
Authors:Greasley, S.E., Hickey, M., Ferre, R.-A., Krauss, M., Cronin, C.
Deposit date:2011-05-09
Release date:2011-11-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Discovery of Novel, Potent, and Selective Inhibitors of 3-Phosphoinositide-Dependent Kinase (PDK1).
J.Med.Chem., 54, 2011
3ZX0
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NTPDASE1 IN COMPLEX WITH HEPTAMOLYBDATE
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1, CHLORIDE ION, ACETIC ACID, ...
Authors:Zebisch, M., Schaefer, P., Straeter, N.
Deposit date:2011-08-04
Release date:2011-11-30
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1.
J. Mol. Biol., 415, 2012
3ZX2
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NTPDASE1 IN COMPLEX WITH DECAVANADATE
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1, CHLORIDE ION, ACETIC ACID, ...
Authors:Zebisch, M., Schaefer, P., Straeter, N.
Deposit date:2011-08-04
Release date:2011-11-30
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1.
J.Mol.Biol., 415, 2012
3ZX3
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CRYSTAL STRUCTURE AND DOMAIN ROTATION OF NTPDASE1 CD39
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1, CHLORIDE ION, ACETIC ACID, ...
Authors:Zebisch, M., Schaefer, P., Straeter, N.
Deposit date:2011-08-04
Release date:2011-11-30
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1.
J.Mol.Biol., 415, 2012
4A57
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3)
Descriptor:NUCLEOSIDE-TRIPHOSPHATASE 1, CHLORIDE ION
Authors:Krug, U., Zebisch, M., Straeter, N.
Deposit date:2011-10-24
Release date:2011-11-30
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
J.Biol.Chem., 287, 2012
4A59
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3) IN COMPLEX WITH AMP
Descriptor:NUCLEOSIDE-TRIPHOSPHATASE 1, ADENOSINE MONOPHOSPHATE
Authors:Krug, U., Zebisch, M., Straeter, N.
Deposit date:2011-10-24
Release date:2011-11-30
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
J.Biol.Chem., 287, 2012
4A5A
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CRYSTAL STRUCTURE OF THE C258S/C268S VARIANT OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3) IN COMPLEX WITH MAGNESIUM AND AMPPNP
Descriptor:NUCLEOSIDE-TRIPHOSPHATASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Krug, U., Zebisch, M., Straeter, N.
Deposit date:2011-10-24
Release date:2011-11-30
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
J.Biol.Chem., 287, 2012
4A5B
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CRYSTAL STRUCTURE OF THE C258S/C268S VARIANT OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 (NTPDASE1)
Descriptor:NUCLEOSIDE-TRIPHOSPHATASE 2
Authors:Krug, U., Zebisch, M., Strater, N.
Deposit date:2011-10-24
Release date:2011-11-30
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Insight Into Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
J.Biol.Chem., 287, 2012
4BQZ
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RAT NTPDASE2 IN COMPLEX WITH MG GMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-03
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR0
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RAT NTPDASE2 IN COMPLEX WITH CA AMPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2, 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, CALCIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-03
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR2
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RAT NTPDASE2 IN COMPLEX WITH CA UMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2, 5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]uridine, CALCIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-03
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR4
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM I, OPEN, APO
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, CHLORIDE ION, MAGNESIUM ION
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-03
Release date:2013-07-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR5
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RAT NTPDASE2 IN COMPLEX WITH ZN AMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR7
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM I, OPEN, AMPNP COMPLEX
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, MAGNESIUM ION, 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BR9
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II, CLOSED, APO
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, SULFATE ION, GLYCEROL
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRA
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II, CLOSED, MG AMPPNP COMPLEX
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRC
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II, CLOSED, MG AMPNP COMPLEX
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRD
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LEGIONELLA PNEUMOPHILA NTPDASE1 Q193E CRYSTAL FORM II, CLOSED, MG AMPPNP COMPLEX
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRE
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II (CLOSED) IN COMPLEX WITH TRANSITION STATE MIMIC ADENOSINE 5'PHOSPHOVANADATE
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, SODIUM ION, ADENOSINE-5'-PHOSPHOVANADATE, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRF
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II (CLOSED) IN COMPLEX WITH A DISTORTED ORTHOMOLYBDATE ION AND AMP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, MOLYBDATE ION, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRG
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II (CLOSED) IN COMPLEX WITH MG GMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRH
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II (CLOSED) IN COMPLEX WITH MG AND THIAMINE PHOSPHOVANADATE
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, THIAMINE-PHOSPHOVANADATE, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases.
Structure, 21, 2013
4BRI
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LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II (CLOSED) IN COMPLEX WITH MG UMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, 5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]uridine, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
4BRK
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LEGIONELLA PNEUMOPHILA NTPDASE1 N302Y VARIANT CRYSTAL FORM III (CLOSED) IN COMPLEX WITH MG UMPPNP
Descriptor:ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE I, 5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]uridine, MAGNESIUM ION, ...
Authors:Zebisch, M., Schaefer, P., Lauble, P., Straeter, N.
Deposit date:2013-06-04
Release date:2013-07-17
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
Structure, 21, 2013
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