4A5A

Crystal structure of the C258S/C268S variant of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) in complex with magnesium and AMPPNP

Summary for 4A5A

Entry DOI	10.2210/pdb4a5a/pdb
Related	4A57 4A59 4A5B
Descriptor	NUCLEOSIDE-TRIPHOSPHATASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total)
Functional Keywords	hydrolase, ntpdase
Biological source	TOXOPLASMA GONDII
Cellular location	Secreted: Q27893
Total number of polymer chains	4
Total formula weight	272625.16
Authors	Krug, U.,Zebisch, M.,Straeter, N. (deposition date: 2011-10-24, release date: 2011-11-30, Last modification date: 2023-12-20)
Primary citation	Krug, U.,Zebisch, M.,Krauss, M.,Straeter, N. Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction. J.Biol.Chem., 287:3051-, 2012 Cited by PubMed: 22130673 DOI: 10.1074/JBC.M111.294348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation