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5VC7
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BU of 5vc7 by Molmil
VCP like ATPase from T. acidophilum (VAT) - conformation 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, VCP-like ATPase
Authors:Ripstein, Z.A, Huang, R, Augustyniak, R, Kay, L.E, Rubinstein, J.L.
Deposit date:2017-03-31
Release date:2017-04-26
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of a AAA+ unfoldase in the process of unfolding substrate.
Elife, 6, 2017
6DKF
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BU of 6dkf by Molmil
Caseinolytic protease (ClpP) from Staphylococcus aureus mutant - V7A
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Ripstein, Z.A, Vahidi, S, Kay, L.E, Rubinstein, J.L.
Deposit date:2018-05-29
Release date:2018-06-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Reversible inhibition of the ClpP protease via an N-terminal conformational switch.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VCA
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BU of 5vca by Molmil
VCP like ATPase from T. acidophilum (VAT)-Substrate bound conformation
Descriptor: VCP-like ATPase
Authors:Ripstein, Z.A, Huang, R, Augustyniak, R, Kay, L.E, Rubinstein, J.L.
Deposit date:2017-03-31
Release date:2017-04-26
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of a AAA+ unfoldase in the process of unfolding substrate.
Elife, 6, 2017
8UX1
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BU of 8ux1 by Molmil
Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
Descriptor: 153-bp Widom 601 DNA forward strand, 153-bp Widom 601 DNA reverse strand, GTP-binding nuclear protein Ran, ...
Authors:Huang, S.K, Rubinstein, J.L, Kay, L.E.
Deposit date:2023-11-08
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
To Be Published
1Y8B
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BU of 1y8b by Molmil
Solution NMR-Derived Global Fold of Malate Synthase G from E.coli
Descriptor: Malate synthase G
Authors:Tugarinov, V, Choy, W.-Y, Orekhov, V.Y, Kay, L.E.
Deposit date:2004-12-10
Release date:2005-01-11
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Solution NMR-derived global fold of a monomeric 82-kDa enzyme.
Proc.Natl.Acad.Sci.USA, 102, 2005
1DDM
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BU of 1ddm by Molmil
SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE
Descriptor: NUMB ASSOCIATE KINASE, NUMB PROTEIN
Authors:Zwahlen, C, Li, S.C, Kay, L.E, Pawson, T, Forman-Kay, J.D.
Deposit date:1999-11-11
Release date:2000-04-10
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb.
EMBO J., 19, 2000
5G4F
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BU of 5g4f by Molmil
Structure of the ADP-bound VAT complex
Descriptor: VCP-LIKE ATPASE
Authors:Huang, R, Ripstein, Z.A, Augustyniak, R, Lazniewski, M, Ginalski, K, Kay, L.E, Rubinstein, J.L.
Deposit date:2016-05-12
Release date:2016-07-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Unfolding the Mechanism of the Aaa+ Unfoldase Vat by a Combined Cryo-Em, Solution NMR Study.
Proc.Natl.Acad.Sci.USA, 113, 2016
5G4G
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BU of 5g4g by Molmil
Structure of the ATPgS-bound VAT complex
Descriptor: VCP-LIKE ATPASE
Authors:Huang, R, Ripstein, Z.A, Augustyniak, R, Lazniewski, M, Ginalski, K, Kay, L.E, Rubinstein, J.L.
Deposit date:2016-05-12
Release date:2016-07-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Unfolding the Mechanism of the Aaa+ Unfoldase Vat by a Combined Cryo-Em, Solution NMR Study.
Proc.Natl.Acad.Sci.USA, 113, 2016
2JQX
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BU of 2jqx by Molmil
Solution structure of Malate Synthase G from joint refinement against NMR and SAXS data
Descriptor: Malate synthase G
Authors:Grishaev, A, Tugarinov, V, Kay, L.E, Trewhella, J, Bax, A.
Deposit date:2007-06-13
Release date:2007-07-10
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Refined solution structure of the 82-kDa enzyme malate synthase G from joint NMR and synchrotron SAXS restraints
J.Biomol.Nmr, 40, 2008
2IL6
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BU of 2il6 by Molmil
HUMAN INTERLEUKIN-6, NMR, 32 STRUCTURES
Descriptor: INTERLEUKIN-6
Authors:Xu, G.Y, Yu, H.A, Hong, J, Stahl, M, Mcdonagh, T, Kay, L.E, Cumming, D.A.
Deposit date:1997-01-31
Release date:1998-02-04
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of recombinant human interleukin-6.
J.Mol.Biol., 268, 1997
1KA7
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BU of 1ka7 by Molmil
SAP/SH2D1A bound to peptide n-Y-c
Descriptor: SH2 DOMAIN PROTEIN 1A, peptide n-Y-c
Authors:Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
Deposit date:2001-10-31
Release date:2001-11-07
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
1KA6
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BU of 1ka6 by Molmil
SAP/SH2D1A bound to peptide n-pY
Descriptor: SH2 DOMAIN PROTEIN 1A, peptide n-pY
Authors:Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
Deposit date:2001-10-31
Release date:2001-11-07
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
1MM4
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BU of 1mm4 by Molmil
Solution NMR structure of the outer membrane enzyme PagP in DPC micelles
Descriptor: CrcA protein
Authors:Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E.
Deposit date:2002-09-03
Release date:2002-09-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR
Proc.Natl.Acad.Sci.USA, 99, 2002
1EZO
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BU of 1ezo by Molmil
GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN
Authors:Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E.
Deposit date:2000-05-11
Release date:2001-05-03
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein.
J.Mol.Biol., 300, 2000
1EZP
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BU of 1ezp by Molmil
GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS
Descriptor: MALTODEXTRIN BINDING PERIPLASMIC PROTEIN
Authors:Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E.
Deposit date:2000-05-11
Release date:2001-05-08
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein.
J.Mol.Biol., 300, 2000
1MM5
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BU of 1mm5 by Molmil
Solution NMR structure of the outer membrane enzyme PagP in OG micelles
Descriptor: CrcA protein
Authors:Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E.
Deposit date:2002-09-03
Release date:2002-09-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR
Proc.Natl.Acad.Sci.USA, 99, 2002
1JU5
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BU of 1ju5 by Molmil
Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy
Descriptor: Abl, Crk
Authors:Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D.
Deposit date:2001-08-23
Release date:2002-11-06
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99, 2002
2KIS
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BU of 2kis by Molmil
Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker
Descriptor: Transcription elongation regulator 1
Authors:Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T.
Deposit date:2009-05-08
Release date:2009-09-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
J.Mol.Biol., 393, 2009
2PLE
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BU of 2ple by Molmil
NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
Descriptor: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
Authors:Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
Deposit date:1994-08-19
Release date:1995-01-26
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
2PLD
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BU of 2pld by Molmil
NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
Descriptor: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
Authors:Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
Deposit date:1994-08-19
Release date:1995-01-26
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
1IL6
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BU of 1il6 by Molmil
HUMAN INTERLEUKIN-6, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: INTERLEUKIN-6
Authors:Xu, G.Y, Yu, H.A, Hong, J, Stahl, M, Mcdonagh, T, Kay, L.E, Cumming, D.A.
Deposit date:1997-01-31
Release date:1998-02-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of recombinant human interleukin-6.
J.Mol.Biol., 268, 1997
8F0U
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BU of 8f0u by Molmil
Structure of a 12mer DegP cage bound to the client protein hTRF1
Descriptor: Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1
Authors:Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E.
Deposit date:2022-11-04
Release date:2022-11-23
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
8F26
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BU of 8f26 by Molmil
Structure of a 60mer DegP cage bound to the client protein hTRF1
Descriptor: Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1
Authors:Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E.
Deposit date:2022-11-07
Release date:2022-11-23
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
8F21
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BU of 8f21 by Molmil
Structure of a 30mer DegP cage bound to the client protein hTRF1
Descriptor: Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1
Authors:Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E.
Deposit date:2022-11-06
Release date:2022-11-23
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023
8F0A
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BU of 8f0a by Molmil
Client-bound structure of a DegP trimer within a 12mer cage
Descriptor: Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1
Authors:Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E.
Deposit date:2022-11-02
Release date:2022-11-23
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
J.Am.Chem.Soc., 145, 2023

 

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