Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2A0F
DownloadVisualize
BU of 2a0f by Molmil
Structure of D236A mutant E. coli Aspartate Transcarbamoylase in presence of Phosphonoacetamide at 2.90 A resolution
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHONOACETAMIDE, ...
Authors:Stieglitz, K.A, Dusinberre, K.J, Cardia, J.P, Tsuruta, H, Kantrowitz, E.R.
Deposit date:2005-06-16
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the E.coli Aspartate Transcarbamoylase Trapped in the Middle of the Catalytic Cycle.
J.Mol.Biol., 352, 2005
3MPU
DownloadVisualize
BU of 3mpu by Molmil
Crystal structure of the C47A/A241C disulfide-linked E. coli Aspartate Transcarbamoylase holoenzyme
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHATE ION, ...
Authors:Mendes, K.R, Kantrowitz, E.R.
Deposit date:2010-04-27
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.855 Å)
Cite:The Pathway of Product Release from the R State of Aspartate Transcarbamoylase.
J.Mol.Biol., 401, 2010
1HQA
DownloadVisualize
BU of 1hqa by Molmil
ALKALINE PHOSPHATASE (H412Q)
Descriptor: ALKALINE PHOSPHATASE, ZINC ION
Authors:Ma, L, Kantrowitz, E.R.
Deposit date:1995-11-30
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites.
Biochemistry, 35, 1996
1HJK
DownloadVisualize
BU of 1hjk by Molmil
ALKALINE PHOSPHATASE MUTANT H331Q
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Murphy, J.E, Stec, B, Ma, L, Kantrowitz, E.R.
Deposit date:1997-05-30
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Trapping and visualization of a covalent enzyme-phosphate intermediate.
Nat.Struct.Biol., 4, 1997
1ACM
DownloadVisualize
BU of 1acm by Molmil
ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, ...
Authors:Stevens, R.C, Kantrowitz, E.R, Lipscomb, W.N.
Deposit date:1992-07-08
Release date:1992-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
Protein Sci., 1, 1992
2ANH
DownloadVisualize
BU of 2anh by Molmil
ALKALINE PHOSPHATASE (D153H)
Descriptor: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
Authors:Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
1ANJ
DownloadVisualize
BU of 1anj by Molmil
ALKALINE PHOSPHATASE (K328H)
Descriptor: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
Authors:Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
1ANI
DownloadVisualize
BU of 1ani by Molmil
ALKALINE PHOSPHATASE (D153H, K328H)
Descriptor: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
Authors:Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
1URA
DownloadVisualize
BU of 1ura by Molmil
ALKALINE PHOSPHATASE (D51ZN)
Descriptor: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
Authors:Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R.
Deposit date:1996-02-03
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 257, 1996
1URB
DownloadVisualize
BU of 1urb by Molmil
ALKALINE PHOSPHATASE (N51MG)
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R.
Deposit date:1996-02-03
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 257, 1996
1ALI
DownloadVisualize
BU of 1ali by Molmil
ALKALINE PHOSPHATASE MUTANT (H412N)
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-06-02
Release date:1995-11-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
1ALJ
DownloadVisualize
BU of 1alj by Molmil
ALKALINE PHOSPHATASE MUTANT (H412N)
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-06-02
Release date:1995-11-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
3D7S
DownloadVisualize
BU of 3d7s by Molmil
Crystal structure of Wild-Type E. Coli Asparate Transcarbamoylase at pH 8.5 at 2.80 A Resolution
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:Stieglitz, K.A, Xia, J, Kantrowitz, E.R.
Deposit date:2008-05-21
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The first high pH structure of Escherichia coli aspartate transcarbamoylase.
Proteins, 74, 2008
1B8J
DownloadVisualize
BU of 1b8j by Molmil
ALKALINE PHOSPHATASE COMPLEXED WITH VANADATE
Descriptor: MAGNESIUM ION, PROTEIN (ALKALINE PHOSPHATASE), SULFATE ION, ...
Authors:Holtz, K.M, Stec, B, Kantrowitz, E.R.
Deposit date:1999-02-01
Release date:1999-02-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A model of the transition state in the alkaline phosphatase reaction.
J.Biol.Chem., 274, 1999
1NBE
DownloadVisualize
BU of 1nbe by Molmil
ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN MUTANT (T82A)
Descriptor: ASPARTATE TRANSCARBAMOYLASE, D-MALATE, ZINC ION
Authors:Williams, M.K, Stec, B, Kantrowitz, E.R.
Deposit date:1998-04-25
Release date:1998-10-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A single mutation in the regulatory chain of Escherichia coli aspartate transcarbamoylase results in an extreme T-state structure.
J.Mol.Biol., 281, 1998
2QGF
DownloadVisualize
BU of 2qgf by Molmil
Structure of regulatory chain mutant H20A of asparate transcarbamoylase from E. coli
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:Stec, B, Williams, M.K, Stieglitz, K.A, Kantrowitz, E.R.
Deposit date:2007-06-28
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors.
Acta Crystallogr.,Sect.D, 63, 2007
1I5O
DownloadVisualize
BU of 1i5o by Molmil
CRYSTAL STRUCTURE OF MUTANT R105A OF E. COLI ASPARTATE TRANSCARBAMOYLASE
Descriptor: ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN, ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
Authors:Macol, C.P, Tsuruta, H, Stec, B, Kantrowitz, E.R.
Deposit date:2001-02-28
Release date:2001-05-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Direct structural evidence for a concerted allosteric transition in Escherichia coli aspartate transcarbamoylase.
Nat.Struct.Biol., 8, 2001
2QG9
DownloadVisualize
BU of 2qg9 by Molmil
Structure of a regulatory subunit mutant D19A of ATCase from E. coli
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:Stec, B, Williams, M.K, Stieglitz, K.A, Kantrowitz, E.R.
Deposit date:2007-06-28
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors.
Acta Crystallogr.,Sect.D, 63, 2007
4KH1
DownloadVisualize
BU of 4kh1 by Molmil
The R state structure of E. coli ATCase with CTP,UTP, and Magnesium bound
Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
Deposit date:2013-04-29
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
4KH0
DownloadVisualize
BU of 4kh0 by Molmil
The R state structure of E. coli ATCase with ATP and Magnesium bound
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ...
Authors:Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
Deposit date:2013-04-29
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
4KGZ
DownloadVisualize
BU of 4kgz by Molmil
The R state structure of E. coli ATCase with UTP and Magnesium bound
Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, MAGNESIUM ION, ...
Authors:Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
Deposit date:2013-04-29
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
4KGX
DownloadVisualize
BU of 4kgx by Molmil
The R state structure of E. coli ATCase with CTP bound
Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
Deposit date:2013-04-29
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
4KGV
DownloadVisualize
BU of 4kgv by Molmil
The R state structure of E. coli ATCase with ATP bound
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ...
Authors:Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
Deposit date:2013-04-29
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
1EW9
DownloadVisualize
BU of 1ew9 by Molmil
ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH MERCAPTOMETHYL PHOSPHONATE
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, MERCAPTOMETHYL PHOSPHONATE, ...
Authors:Holtz, K.M, Stec, B, Meyers, J.K, Antonelli, S.M, Widlanski, T.S, Kantrowitz, E.R.
Deposit date:2000-04-24
Release date:2002-05-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
Protein Sci., 9, 2000
1FSA
DownloadVisualize
BU of 1fsa by Molmil
THE T-STATE STRUCTURE OF LYS 42 TO ALA MUTANT OF THE PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ...
Authors:Lu, G, Stec, B, Giroux, E, Kantrowitz, E.R.
Deposit date:1996-08-24
Release date:1997-09-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evidence for an active T-state pig kidney fructose 1,6-bisphosphatase: interface residue Lys-42 is important for allosteric inhibition and AMP cooperativity.
Protein Sci., 5, 1996

 

1234>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon