3MPU

Crystal structure of the C47A/A241C disulfide-linked E. coli Aspartate Transcarbamoylase holoenzyme

Summary for 3MPU

• Entry DOI: 10.2210/pdb3mpu/pdb
• Related: 1AT1 1D09 1R0B 1ZA2 2A0F
• Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: aspartate trancarbamoylase, disulfide bond, phosphate, catalysis, product release, ordered-sequential mechanism, transferase
• Biological source: Escherichia coli; More
• Total number of polymer chains: 6
• Total formula weight: 155208.24

Authors

Mendes, K.R.,Kantrowitz, E.R. (deposition date: 2010-04-27, release date: 2010-07-21, Last modification date: 2023-09-06)

• Primary citation: Mendes, K.R.,Kantrowitz, E.R.; The Pathway of Product Release from the R State of Aspartate Transcarbamoylase.; J.Mol.Biol., 401:940-948, 2010; PubMed: 20620149; DOI: 10.1016/j.jmb.2010.07.003

Experimental method

X-RAY DIFFRACTION (2.855 Å)