3MPU
Crystal structure of the C47A/A241C disulfide-linked E. coli Aspartate Transcarbamoylase holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Aspartate carbamoyltransferase catalytic chain | polymer | 310 | 34337.1 | 3 | UniProt (P0A786) Pfam (PF02729) Pfam (PF00185) | Escherichia coli | Aspartate transcarbamylase, ATCase |
| 2 | B, D, F (B, D, F) | Aspartate carbamoyltransferase regulatory chain | polymer | 153 | 17143.6 | 3 | UniProt (P0A7F3) Pfam (PF01948) Pfam (PF02748) | Escherichia coli | |
| 3 | G, H, J, K, M... (A, C, E) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 4 | I, L, O (B, D, F) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | P, Q, R, S, T... (A, B, C, D, E...) | water | water | 18.0 | 734 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 310 (UniProt: P0A786)
| PDB | External Database | Details |
|---|---|---|
| Ala 47 | Cys 48 | engineered mutation |
| Cys 241 | Ala 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 154442.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 766.1 | |
| All* | Total formula weight | 155208.2 |
