2A0F

Structure of D236A mutant E. coli Aspartate Transcarbamoylase in presence of Phosphonoacetamide at 2.90 A resolution

Summary for 2A0F

Entry DOI	10.2210/pdb2a0f/pdb
Related	1D09 8AT1
Descriptor	Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHONOACETAMIDE, ... (5 entities in total)
Functional Keywords	homotropic cooperativity, catalytic cycle, allosteric regulation, alternate conformations, transferase-transferase regulator complex, transferase/transferase regulator
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	103143.31
Authors	Stieglitz, K.A.,Dusinberre, K.J.,Cardia, J.P.,Tsuruta, H.,Kantrowitz, E.R. (deposition date: 2005-06-16, release date: 2005-09-27, Last modification date: 2023-08-23)
Primary citation	Stieglitz, K.A.,Dusinberre, K.J.,Cardia, J.P.,Tsuruta, H.,Kantrowitz, E.R. Structure of the E.coli Aspartate Transcarbamoylase Trapped in the Middle of the Catalytic Cycle. J.Mol.Biol., 352:478-486, 2005 Cited by PubMed: 16120448 DOI: 10.1016/j.jmb.2005.07.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation