2QGF

Structure of regulatory chain mutant H20A of asparate transcarbamoylase from E. coli

Summary for 2QGF

• Entry DOI: 10.2210/pdb2qgf/pdb
• Related: 2QG9 6AT1
• Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION, ... (4 entities in total)
• Functional Keywords: allosteric enzyme regulatory chain mutation, heterotropic regulation, transferase-transferase regulator complex, transferase/transferase regulator
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 102958.14

Authors

Stec, B.,Williams, M.K.,Stieglitz, K.A.,Kantrowitz, E.R. (deposition date: 2007-06-28, release date: 2008-02-19, Last modification date: 2023-08-30)

• Primary citation: Stec, B.,Williams, M.K.,Stieglitz, K.A.,Kantrowitz, E.R.; Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors.; Acta Crystallogr.,Sect.D, 63:1243-1253, 2007; PubMed: 18084072; DOI: 10.1107/S0907444907052985

Experimental method

X-RAY DIFFRACTION (2.2 Å)