Author results

4GW1
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CQFD MEDITOPE
Descriptor:Fab light chain, Fab heavy chain, cQFD meditope, ...
Authors:Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GW5
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CQYN MEDITOPE - CETUXIMAB FAB
Descriptor:Fab Light Chain, Fab Heavy Chain, cQYN meditope, ...
Authors:Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJG
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MEDITOPE-ENABLED TRASTUZUMAB
Descriptor:Trastuzumab light chain, Trastuzumab heavy chain, Immunoglobulin G-binding protein A, ...
Authors:Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C.
Deposit date:2012-10-12
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
4HKZ
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TRASTUZUMAB FAB COMPLEXED WITH PROTEIN L AND PROTEIN A FRAGMENTS
Descriptor:Trastuzumab light chain, Trastuzumab heavy chain, Immunoglobulin G-binding protein A, ...
Authors:Avery, K.N., Zer, C., Bzymek, K.P., Williams, J.C.
Deposit date:2012-10-15
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IOI
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MEDITOPE-ENABLED TRASTUZUMAB IN COMPLEX WITH CQFDLSTRRLKC
Descriptor:Trastuzumab light chain, Trastuzumab heavy chain, Immunoglobulin G-binding protein A, ...
Authors:Bzymek, K.P., Zer, C., Avery, K.N., Williams, J.C.
Deposit date:2013-01-07
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5ESQ
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CETUXIMAB FAB IN COMPLEX WITH CYCLIC BETA-ALANINE-LINKED MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Cyclic beta-alanine-linked meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2015-11-16
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ETU
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CETUXIMAB FAB IN COMPLEX WITH L5E MEDITOPE VARIANT
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, L5E meditope variant, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2015-11-18
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5EUK
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CETUXIMAB FAB IN COMPLEX WITH F3H MEDITOPE VARIANT
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, F3H meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2015-11-18
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5F88
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CETUXIMAB FAB IN COMPLEX WITH L5Y MEDITOPE VARIANT
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, L5Y meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2015-12-09
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5FF6
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CETUXIMAB FAB IN COMPLEX WITH L10Q MEDITOPE VARIANT
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, L10Q meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2015-12-17
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HPM
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CETUXIMAB FAB IN COMPLEX WITH CYCLIC LINKED MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Cyclic amidated, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-01-20
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HYQ
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CETUXIMAB FAB IN COMPLEX WITH AMIDATED MEDITOPE
Descriptor:Cetuximab light chain, Cetuximab heavy chain, Amidated meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-01
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5I2I
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STRUCTURE OF CETUXIMAB FAB WITH CYCLIC F3Q VARIANT OF THE MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-08
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICX
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CETUXIMAB FAB IN COMPLEX WITH CQFDLSTRRLRCGGSK MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICY
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CETUXIMAB FAB IN COMPLEX WITH LINEAR MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICZ
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CETUXIMAB FAB IN COMPLEX WITH GQFDLSTRRLKG PEPTIDE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID0
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CETUXIMAB FAB IN COMPLEX WITH AMINOHEPTANOIC ACID-LINKED MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Cyclic meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID1
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CETUXIMAB FAB IN COMPLEX WITH MPT-CYS MEDITOPE
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IOP
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CETUXIMAB FAB IN COMPLEX WITH 4-BROMOPHENYLALANINE MEDITOPE VARIANT
Descriptor:Cetuximab Fab, light chain, heavy chain, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-03-08
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IR1
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CETUXIMAB FAB IN COMPLEX WITH 3-BROMOPHENYLALANINE MEDITOPE VARIANT
Descriptor:Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope variant, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-03-11
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ITF
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CETUXIMAB FAB IN COMPLEX WITH 2-BROMOPHENYLALANINE MEDITOPE VARIANT
Descriptor:Cetuximab Fab, light chain, heavy chain, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IV2
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CETUXIMAB FAB IN COMPLEX WITH ARG9CIR MEDITOPE VARIANT
Descriptor:Cetuximab Fab, light chain, heavy chain, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-03-18
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IVZ
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CETUXIMAB FAB IN COMPLEX WITH ARG8CIR MEDITOPE VARIANT
Descriptor:Cetuximab Fab, light chain, heavy chain, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-03-21
Release date:2016-10-26
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5T1K
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CETUXIMAB FAB IN COMPLEX WITH CQFDA(PH)2STRRLKC
Descriptor:CETUXIMAB FAB LIGHT CHAIN, CETUXIMAB FAB HEAVY CHAIN, CQFDA(PH)2STRRLKC PEPTIDE, ...
Authors:Bzymek, K.P., Williams, J.C.
Deposit date:2016-08-19
Release date:2016-10-26
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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