5ICX

Cetuximab Fab in complex with CQFDLSTRRLRCGGSK meditope

Summary for 5ICX

• Entry DOI: 10.2210/pdb5icx/pdb
• Related: 4GW1 5ESQ 5ETU 5EUK 5F88 5FF6 5HPM 5HYQ 5I2I 5ICY 5ICZ 5ID0 5ID1
• Descriptor: Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ... (6 entities in total)
• Functional Keywords: antibody, anti-egfr, immune system
• Biological source: MUS MUSCULUS, HOMO SAPIENS (mouse, human); More
• Total number of polymer chains: 6
• Total formula weight: 98373.85

Authors

Bzymek, K.P.,Williams, J.C. (deposition date: 2016-02-23, release date: 2016-06-15, Last modification date: 2023-09-27)

• Primary citation: Bzymek, K.P.,Ma, Y.,Avery, K.A.,Horne, D.A.,Williams, J.C.; Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.; Acta Crystallogr F Struct Biol Commun, 72:434-442, 2016; PubMed: 27303895; DOI: 10.1107/S2053230X16007202

Experimental method

X-RAY DIFFRACTION (2.6 Å)