5ICY

Cetuximab Fab in complex with linear meditope

Summary for 5ICY

Entry DOI	10.2210/pdb5icy/pdb
Related	1YY8 4GW1 4GW5 4HBB 5ESQ 5ETU 5EUK 5F88 5FF6 5HPM 5HYQ 5I2I 5ICX 5ICZ 5ID0 5ID1
Descriptor	Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope, ... (5 entities in total)
Functional Keywords	antibody, anti-egfr, immune system
Biological source	MUS MUSCULUS, HOMO SAPIENS More
Total number of polymer chains	6
Total formula weight	97538.41
Authors	Bzymek, K.P.,Williams, J.C. (deposition date: 2016-02-23, release date: 2016-06-15, Last modification date: 2023-09-27)
Primary citation	Bzymek, K.P.,Ma, Y.,Avery, K.A.,Horne, D.A.,Williams, J.C. Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72:434-442, 2016 Cited by PubMed: 27303895 DOI: 10.1107/S2053230X16007202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation