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1LNA
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Hausrath, A.C., Juers, D., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNB
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Hausrath, A.C., Juers, D., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNC
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Hausrath, A.C., Juers, D., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LND
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Hausrath, A.C., Juers, D., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNE
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Hausrath, A.C., Juers, D., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNF
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A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Holland, D.R., Matthews, B.W.
Deposit date:1994-05-13
Release date:1995-05-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1BKL
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SELF-ASSOCIATED APO SRC SH2 DOMAIN
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-05-02
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel Pp60Src Sh2 Domain Crystal Structures: A 2.0 Angstrom Co-Crystal Structure of a D-Amino Acid Substituted Phosphopeptide Complex and a 2.1 Angstrom Apo Structure Displaying Self-Association
To be Published
1BKM
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COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, [[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-05-02
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain
J.Am.Chem.Soc., 119, 1997
1BTG
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CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND
Descriptor:BETA NERVE GROWTH FACTOR, ZINC ION
Authors:Holland, D.R., Matthews, B.W.
Deposit date:1995-08-29
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.
J.Mol.Biol., 239, 1994
1PPA
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THE CRYSTAL STRUCTURE OF A LYSINE 49 PHOSPHOLIPASE A2 FROM THE VENOM OF THE COTTONMOUTH SNAKE AT 2.0 ANGSTROMS RESOLUTION
Descriptor:PHOSPHOLIPASE A2, ANILINE
Authors:Holland, D.R., Clancy, L.L., Muchmore, S.W., Rydel, T.J., Einspahr, H.M., Finzel, B.C., Heinrikson, R.L., Watenpaugh, K.D.
Deposit date:1991-10-29
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution.
J.Biol.Chem., 265, 1990
1THL
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THERMOLYSIN COMPLEXED WITH A NOVEL GLUTARAMIDE DERIVATIVE, N-(1-(2(R,S)-CARBOXY-4-PHENYLBUTYL) CYCLOPENTYLCARBONYL)-(S)-TRYPTOPHAN
Descriptor:THERMOLYSIN, CALCIUM ION, ZINC ION, ...
Authors:Holland, D.R., Matthews, B.W.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex
Biochemistry, 33, 1994
1LSM
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THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Holland, D.R., Shih, P.
Deposit date:1994-09-13
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules.
Protein Sci., 4, 1995
1LSN
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THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
Descriptor:HEN EGG WHITE LYSOZYME
Authors:Holland, D.R., Shih, P.
Deposit date:1994-09-13
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules.
Protein Sci., 4, 1995
1SKJ
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COCRYSTAL STRUCTURE OF UREA-SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, 4-[3-CARBOXYMETHYL-3-(4-PHOSPHONOOXY-BENZYL)-UREIDO]-4-[(3-CYCLOHEXYL-PROPYL)-METHYL-CARBAMOYL]BUTYRIC ACID
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-09-18
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand.
J.Med.Chem., 40, 1997
8TLN
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STRUCTURAL COMPARISON SUGGESTS THAT THERMOLYSIN AND RELATED NEUTRAL PROTEASES UNDERGO HINGE-BENDING MOTION DURING CATALYSIS
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:Tronrud, D., Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.
Biochemistry, 31, 1992
1I1B
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-1BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 BETA
Authors:Finzel, B.C., Watenpaugh, K.D., Einspahr, H.M.
Deposit date:1989-12-05
Release date:1990-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution.
J.Mol.Biol., 209, 1989
1QF0
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-PHE-TYR. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
Descriptor:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
Authors:Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
Deposit date:1999-04-06
Release date:1999-12-29
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1QF1
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYLHEPTANOYL)-PHE-ALA. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
Descriptor:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
Authors:Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
Deposit date:1999-04-06
Release date:1999-12-29
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1QF2
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THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-GLY-(5-PHENYLPROLINE). PARAMETERS FOR ZN-MONODENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE
Descriptor:PROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ...
Authors:Gaucher, J.-F., Selkti, M., Tiraboschi, G., Prange, T., Roques, B.P., Tomas, A., Fournie-Zaluski, M.C.
Deposit date:1999-04-06
Release date:1999-12-29
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38, 1999
1TLX
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THERMOLYSIN (NATIVE)
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:English, A.C., Done, S.H., Groom, C.R., Hubbard, R.E.
Deposit date:1998-11-02
Release date:2000-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1U4G
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ELASTASE OF PSEUDOMONAS AERUGINOSA WITH AN INHIBITOR
Descriptor:Elastase, ZINC ION, CALCIUM ION, ...
Authors:Bitto, E., McKay, D.B.
Deposit date:2004-07-25
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Elastase of Pseudomonas aeruginosa with an inhibitor
To be Published, 2004
2TLX
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THERMOLYSIN (NATIVE)
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:English, A.C., Done, S.H., Groom, C.R., Hubbard, R.E.
Deposit date:1999-01-28
Release date:2000-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
3DBK
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PSEUDOMONAS AERUGINOSA ELASTASE WITH PHOSPHORAMIDON
Descriptor:Elastase, ZINC ION, CALCIUM ION, ...
Authors:McKay, D.B., Overgaard, M.T.
Deposit date:2008-06-01
Release date:2009-07-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the Elastase of Pseudomonas aeruginosa Complexed with Phosphoramidon
To be Published