1QF1

THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYLHEPTANOYL)-PHE-ALA. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE

Summary for 1QF1

DescriptorPROTEIN (THERMOLYSIN), ZINC ION, CALCIUM ION, ... (6 entities in total)
Functional Keywordsneutral endopeptidase, zn metallopeptidase, hydrolase
Biological sourceBacillus thermoproteolyticus
Cellular locationSecreted P00800
Total number of polymer chains1
Total molecular weight35124.79
Authors
Gaucher, J.-F.,Selkti, M.,Tiraboschi, G.,Prange, T.,Roques, B.P.,Tomas, A.,Fournie-Zaluski, M.C. (deposition date: 1999-04-06, release date: 1999-12-29, Last modification date: 2018-01-31)
Primary citation
Gaucher, J.F.,Selkti, M.,Tiraboschi, G.,Prange, T.,Roques, B.P.,Tomas, A.,Fournie-Zaluski, M.C.
Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases.
Biochemistry, 38:12569-12576, 1999
PubMed: 10504225 (PDB entries with the same primary citation)
DOI: 10.1021/bi991043z
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.155301.6%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1qf1
no rotation
Molmil generated image of 1qf1
rotated about x axis by 90°
Molmil generated image of 1qf1
rotated about y axis by 90°