1BKM

COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX

Summary for 1BKM

• Entry DOI: 10.2210/pdb1bkm/pdb
• Descriptor: PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, [[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE (3 entities in total)
• Functional Keywords: v-src sh2 domain, phosphotyrosine recognition domain, pp60 src sh2 domain, tripeptide, d-amino acid, transforming protein
• Biological source: Rous sarcoma virus
• Total number of polymer chains: 1
• Total formula weight: 13419.97

Authors

Holland, D.R.,Rubin, J.R. (deposition date: 1997-05-02, release date: 1997-07-07, Last modification date: 2023-08-02)

• Primary citation: Holland, D.R.,Lunney, E.A.,Plummer, M.S.,Mueller, W.T.,Mcconnell, P.,Pavlovsky, A.,Para, K.S.,Shahripour, A.,Humblet, C.,Sawyer, T.K.,Rubin, J.R.; Structure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain; J.Am.Chem.Soc., 119:12471-, 1997

Experimental method

X-RAY DIFFRACTION (2 Å)