Author results

1F5N
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HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.
Descriptor:INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Prakash, B., Renault, L., Praefcke, G.J.K., Herrmann, C., Wittinghofer, A.
Deposit date:2000-06-15
Release date:2000-09-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.
EMBO J., 19, 2000
1I35
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SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF THE PROTEIN KINASE BYR2 FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:PROTEIN KINASE BYR2
Authors:Gronwald, W., Huber, F., Grunewald, P., Sporner, M., Wohlgemuth, S., Herrmann, C., Kalbitzer, H.R.
Deposit date:2001-02-13
Release date:2001-12-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe.
Structure, 9, 2001
2B8W
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF4
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ...
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2B92
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GDP/ALF3
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-10
Release date:2006-03-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2BC9
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH NON-HYDROLYSABLE GTP ANALOGUE GPPNHP
Descriptor:Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
2D4H
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CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF HUMAN GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP
Descriptor:Interferon-induced guanylate-binding protein 1, GUANOSINE-5'-MONOPHOSPHATE
Authors:Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:2005-10-19
Release date:2006-03-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
Nature, 440, 2006
1DG3
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STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM
Descriptor:PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
Authors:Prakash, B., Praefcke, G.J.K., Renault, L., Wittinghofer, A., Herrmann, C.
Deposit date:1999-11-23
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Nature, 403, 2000
1TPZ
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CRYSTAL STRUCTURE OF IIGP1: A PARADIGM FOR INTERFERON INDUCIBLE P47 RESISTANCE GTPASES
Descriptor:interferon-inducible GTPase, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ghosh, A., Uthaiah, R., Howard, J., Herrmann, C., Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ2
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CRYSTAL STRUCTURE OF IIGP1: A PARADIGM FOR INTERFERON INDUCIBLE P47 RESISTANCE GTPASES
Descriptor:interferon-inducible GTPase, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Ghosh, A., Uthaiah, R., Howard, J., Herrmann, C., Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ4
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CRYSTAL STRUCTURE OF IIGP1: A PARADIGM FOR INTERFERON INDUCIBLE P47 RESISTANCE GTPASES
Descriptor:interferon-inducible GTPase, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Ghosh, A., Uthaiah, R., Howard, J., Herrmann, C., Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ6
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CRYSTAL STRUCTURE OF IIGP1: A PARADIGM FOR INTERFERON INDUCIBLE P47 RESISTANCE GTPASES
Descriptor:interferon-inducible GTPase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ghosh, A., Uthaiah, R., Howard, J., Herrmann, C., Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQD
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CRYSTAL STRUCTURE OF IIGP1: A PARADIGM FOR INTERFERON INDUCIBLE P47 RESISTANCE GTPASES
Descriptor:interferon-inducible GTPase, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Ghosh, A., Uthaiah, R., Howard, J., Herrmann, C., Wolf, E.
Deposit date:2004-06-17
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
2B3A
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SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF THE RAL GUANOSINE DISSOCIATION STIMULATOR
Descriptor:Ral guanine nucleotide dissociation stimulator
Authors:Gronwald, W., Maurer, T., Fuechsl, R., Wohlgemuth, S., Herrmann, C., Kalbitzer, H.R.
Deposit date:2005-09-20
Release date:2006-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:New insights into binding of the possible cancer target RalGDS
To be Published
2RGF
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RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES
Descriptor:RALGEF-RBD
Authors:Geyer, M., Herrmann, C., Wittinghofer, A., Kalbitzer, H.R.
Deposit date:1997-02-13
Release date:1998-03-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling.
Nat.Struct.Biol., 4, 1997
2YMY
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STRUCTURE OF THE MURINE NORE1-SARAH DOMAIN
Descriptor:RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5, CADMIUM ION
Authors:Makbul, C., Schwarz, D., Aruxandei, D.C., Wolf, E., Hofmann, E., Herrmann, C.
Deposit date:2012-10-10
Release date:2013-03-20
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and Thermodynamic Characterization of Nore1-Sarah: A Small, Helical Module Important in Signal Transduction Networks.
Biochemistry, 52, 2013
3DDC
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CRYSTAL STRUCTURE OF NORE1A IN COMPLEX WITH RAS
Descriptor:GTPase HRas, Ras association domain-containing family protein 5, MAGNESIUM ION, ...
Authors:Stieglitz, B., Bee, C., Schwarz, D., Yildiz, O., Moshnikova, A., Khokhlatchev, A., Herrmann, C.
Deposit date:2008-06-05
Release date:2008-07-15
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
Embo J., 27, 2008
1IAQ
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C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE
Descriptor:TRANSFORMING PROTEIN P21/H-RAS-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Spoerner, M., Herrmann, C., Vetter, I.R., Kalbitzer, H.R., Wittinghofer, A.
Deposit date:2001-03-23
Release date:2001-06-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dynamic properties of the Ras switch I region and its importance for binding to effectors.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K8R
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CRYSTAL STRUCTURE OF RAS-BRY2RBD COMPLEX
Descriptor:Transforming protein P21/H-RAS-1, Protein kinase byr2, MAGNESIUM ION, ...
Authors:Scheffzek, K., Gruenewald, P., Wohlgemuth, S., Kabsch, W., Tu, H., Wigler, M., Wittinghofer, A., Herrmann, C.
Deposit date:2001-10-25
Release date:2002-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast.
Structure, 9, 2001
1RFH
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SOLUTION STRUCTURE OF THE C1 DOMAIN OF NORE1, A NOVEL RAS EFFECTOR
Descriptor:Ras association (RalGDS/AF-6) domain family 5, ZINC ION
Authors:Guiberman, E., Wohlgemuth, S., Herrmann, C., Harjes, S., Mueller, K.H., Bayer, P.
Deposit date:2003-11-09
Release date:2005-06-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of C1 domain of Nore1
To be Published
2A78
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CRYSTAL STRUCTURE OF THE C3BOT-RALA COMPLEX REVEALS A NOVEL TYPE OF ACTION OF A BACTERIAL EXOENZYME
Descriptor:Ras-related protein Ral-A, Mono-ADP-ribosyltransferase C3, MAGNESIUM ION, ...
Authors:Pautsch, A., Vogelsgesang, M., Trankle, J., Herrmann, C., Aktories, K.
Deposit date:2005-07-05
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
2A9K
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CRYSTAL STRUCTURE OF THE C3BOT-NAD-RALA COMPLEX REVEALS A NOVEL TYPE OF ACTION OF A BACTERIAL EXOENZYME
Descriptor:Ras-related protein Ral-A, Mono-ADP-ribosyltransferase C3, MAGNESIUM ION, ...
Authors:Pautsch, A., Vogelsgesang, M., Trankle, J., Herrmann, C., Aktories, K.
Deposit date:2005-07-12
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
Embo J., 24, 2005
2FNF
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C1 DOMAIN OF NORE1
Descriptor:putative Ras Effector Nore1, ZINC ION
Authors:Harjes, E., Harjes, S., Wohlgemuth, S., Krieger, E., Herrmann, C., Muller, K.H., Bayer, P.
Deposit date:2006-01-11
Release date:2006-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.
Structure, 14, 2006
2WJG
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STRUCTURE AND FUNCTION OF THE FEOB G-DOMAIN FROM METHANOCOCCUS JANNASCHII
Descriptor:FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, POLYALANINE, GUANOSINE-5'-DIPHOSPHATE
Authors:Koester, S., Wehner, M., Herrmann, C., Kuehlbrandt, W., Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii.
J.Mol.Biol., 392, 2009
2WJH
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STRUCTURE AND FUNCTION OF THE FEOB G-DOMAIN FROM METHANOCOCCUS JANNASCHII
Descriptor:FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Koester, S., Wehner, M., Herrmann, C., Kuehlbrandt, W., Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
2WJI
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STRUCTURE AND FUNCTION OF THE FEOB G-DOMAIN FROM METHANOCOCCUS JANNASCHII
Descriptor:FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Koester, S., Wehner, M., Herrmann, C., Kuehlbrandt, W., Yildiz, O.
Deposit date:2009-05-26
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
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