3DDC
Crystal Structure of NORE1A in Complex with RAS
Summary for 3DDC
Entry DOI | 10.2210/pdb3ddc/pdb |
Descriptor | GTPase HRas, Ras association domain-containing family protein 5, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | oncogene, tumorsuppressor, ubiquitin fold, ras effector, rap1, h-ras, rassf1, rassf5, rapl, nore1, gmppnp, adaptor, apoptosis, microtubules, hydrolase-apoptosis complex, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, anti-oncogene, cell cycle, metal-binding, microtubule, phorbol-ester binding, zinc-finger, hydrolase/apoptosis |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 Cytoplasm (By similarity): Q5EBH1 |
Total number of polymer chains | 2 |
Total formula weight | 37884.14 |
Authors | Stieglitz, B.,Bee, C.,Schwarz, D.,Yildiz, O.,Moshnikova, A.,Khokhlatchev, A.,Herrmann, C. (deposition date: 2008-06-05, release date: 2008-07-15, Last modification date: 2023-11-01) |
Primary citation | Stieglitz, B.,Bee, C.,Schwarz, D.,Yildiz, O.,Moshnikova, A.,Khokhlatchev, A.,Herrmann, C. Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Embo J., 27:1995-2005, 2008 Cited by PubMed: 18596699DOI: 10.1038/emboj.2008.125 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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