3DDC
Crystal Structure of NORE1A in Complex with RAS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GTPase HRas | polymer | 166 | 18889.3 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | Transforming protein p21, p21ras, H-Ras-1, c-H-ras, Ha-Ras |
2 | B | Ras association domain-containing family protein 5 | polymer | 163 | 18448.4 | 1 | UniProt (Q5EBH1) Pfam (PF00788) In PDB | Mus musculus (mouse) | New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RAPL, Effector protein NORE1A |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
5 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01112)
B: 200 - 357 (UniProt: Q5EBH1)
PDB | External Database | Details |
---|---|---|
Glu 30 | Asp 30 | engineered mutation |
Lys 31 | Glu 31 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 195 | - | expression tag |
Ser 196 | - | expression tag |
Pro 197 | - | expression tag |
Glu 198 | - | expression tag |
Phe 199 | - | expression tag |
Met 285 | Leu 285 | engineered mutation |
Asp 302 | Lys 302 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37337.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 546.5 | |
All* | Total formula weight | 37884.1 |