Author results

2PVE
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NMR AND X-RAY ANALYSIS OF STRUCTURAL ADDITIVITY IN METAL BINDING SITE-SWAPPED HYBRIDS OF RUBREDOXIN
Descriptor:Rubredoxin, ZINC ION, ACETATE ION, ...
Authors:LeMaster, D.M., Anderson, J.S., Wang, L., Guo, Y., Li, H., Hernandez, G.
Deposit date:2007-05-09
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin.
Bmc Struct.Biol., 7, 2007
2PVX
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NMR AND X-RAY ANALYSIS OF STRUCTURAL ADDITIVITY IN METAL BINDING SITE-SWAPPED HYBRIDS OF RUBREDOXIN
Descriptor:Rubredoxin, ZINC ION
Authors:Wang, L., LeMaster, D.M., Hernandez, G., Li, H.
Deposit date:2007-05-10
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin
Bmc Struct.Biol., 7, 2007
3F1P
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CRYSTAL STRUCTURE OF A HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND ARNT C-TERMINAL PAS DOMAINS
Descriptor:Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator
Authors:Scheuermann, T.H., Tomchick, D.R., Machius, M., Guo, Y., Bruick, R.K., Gardner, K.H.
Deposit date:2008-10-28
Release date:2009-01-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
6MOG
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DIMERIC DARPIN C_R3
Descriptor:DARPin C_R3, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
3L1N
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CRYSTAL STRUCTURE OF MP1P LIGAND BINDING DOMAIN 2 COMPLEXD WITH PALMITIC ACID
Descriptor:Cell wall antigen, PALMITIC ACID
Authors:Liao, S., Tung, E.T., Zheng, W., Chong, K., Xu, Y., Bartlam, M., Rao, Z., Yuen, K.Y.
Deposit date:2009-12-14
Release date:2010-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the Mp1p ligand binding domain 2 reveals its function as a fatty acid-binding protein.
J.Biol.Chem., 285, 2010
4JYP
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CRYSTAL STRUCTURE OF KAI2 APO FORM
Descriptor:Hydrolase, alpha/beta fold family protein
Authors:Guo, Y., Zheng, Z., Noel, J.P.
Deposit date:2013-03-31
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4DFX
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CRYSTAL STRUCTURE OF MYRISTOYLATED K7C CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE IN COMPLEX WITH SP20 AND AMP-PNP
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MYRISTIC ACID, ...
Authors:Bastidas, A.C., Steichen, J.M., Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-06-06
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
4JYM
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CRYSTAL STRUCTURE OF KAI2 IN COMPLEX WITH 3-METHYL-2H-FURO[2,3-C]PYRAN-2-ONE
Descriptor:Hydrolase, alpha/beta fold family protein, 3-methyl-2H-furo[2,3-c]pyran-2-one
Authors:Guo, Y., Zheng, Z., Noel, J.P.
Deposit date:2013-03-30
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ME9
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME3 PEPTIDE
Descriptor:SAGA-associated factor 29 homolog, Histone H3, UNKNOWN ATOM OR ION, ...
Authors:Bian, C., Tempel, W., Xu, C., Guo, Y., Dong, A., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
1Q5Y
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NICKEL-BOUND C-TERMINAL REGULATORY DOMAIN OF NIKR
Descriptor:Nickel responsive regulator, NICKEL (II) ION, 1,2-ETHANEDIOL
Authors:Schreiter, E.R., Sintchak, M.D., Guo, Y., Chivers, P.T., Sauer, R.T., Drennan, C.L.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
5EP6
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THE CRYSTAL STRUCTURE OF NAP1 IN COMPLEX WITH TBK1
Descriptor:5-azacytidine-induced protein 2, Serine/threonine-protein kinase TBK1, GLYCEROL
Authors:Li, F., Xie, X., Liu, J., Pan, L.
Deposit date:2015-11-11
Release date:2016-09-28
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
3F1N
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CRYSTAL STRUCTURE OF A HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND ARNT C-TERMINAL PAS DOMAINS, WITH INTERNALLY BOUND ETHYLENE GLYCOL.
Descriptor:Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, 1,2-ETHANEDIOL
Authors:Scheuermann, T.H., Tomchick, D.R., Machius, M., Guo, Y., Bruick, R.K., Gardner, K.H.
Deposit date:2008-10-28
Release date:2009-01-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.479 Å)
Cite:Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3BKT
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COPPER-BOUND C-TERMINAL DOMAIN OF NIKR
Descriptor:Nickel-responsive regulator, COPPER (II) ION
Authors:Phillips, C.M., Schreiter, E.R., Drennan, C.L.
Deposit date:2007-12-07
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of the Metal Specificity for Nickel Regulatory Protein NikR.
Biochemistry, 47, 2008
4YES
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THROMBIN IN COMPLEX WITH (S)-(4-CHLORO-2-((1-(5-METHYL-1H-PYRROLE-2-CARBONYL)PYRROLIDINE-2-CARBOXAMIDO)METHYL)PHENYL)METHANAMINIUM
Descriptor:Thrombin light chain, Thrombin heavy chain, Hirudin, ...
Authors:Orth, P.
Deposit date:2015-02-24
Release date:2015-06-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement.
Acs Med.Chem.Lett., 6, 2015
5VBT
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CRYSTAL STRUCTURE OF A HIGHLY SPECIFIC AND POTENT USP7 UBIQUITIN VARIANT INHIBITOR
Descriptor:UBH04
Authors:DONG, A., DONG, X., LIU, L., GUO, Y., LI, Y., ZHANG, W., WALKER, J.R., SIDHU, S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., TONG, Y., Structural Genomics Consortium (SGC)
Deposit date:2017-03-30
Release date:2017-06-07
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
1SL4
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CRYSTAL STRUCTURE OF DC-SIGN CARBOHYDRATE RECOGNITION DOMAIN COMPLEXED WITH MAN4
Descriptor:mDC-SIGN1B type I isoform, ALPHA-D-MANNOSE, CALCIUM ION
Authors:Guo, Y., Feinberg, H., Conroy, E., Mitchell, D.A., Alvarez, R., Blixt, O., Taylor, M.E., Weis, W.I., Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
4HPU
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CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE DISPLAYING PARTIAL PHOSPHORYL TRANSFER OF AMP-PNP ONTO A SUBSTRATE PEPTIDE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MYRISTIC ACID, ...
Authors:Bastidas, A.C., Steichen, J.M., Wu, J., Taylor, S.S.
Deposit date:2012-10-24
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Phosphoryl transfer by protein kinase a is captured in a crystal lattice.
J.Am.Chem.Soc., 135, 2013
3F1O
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CRYSTAL STRUCTURE OF THE HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND ARNT C-TERMINAL PAS DOMAINS, WITH AN INTERNALLY-BOUND ARTIFICIAL LIGAND
Descriptor:Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, N-[2-nitro-4-(trifluoromethyl)phenyl]morpholin-4-amine, ...
Authors:Scheuermann, T.H., Tomchick, D.R., Machius, M., Guo, Y., Bruick, R.K., Gardner, K.H.
Deposit date:2008-10-28
Release date:2009-01-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F7M
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CRYSTAL STRUCTURE OF APO CUTICLE-DEGRADING PROTEASE (VER112) FROM VERTICILLIUM PSALLIOTAE
Descriptor:Alkaline serine protease ver112
Authors:Liang, L., Lou, Z., Ye, F., Meng, Z., Rao, Z., Zhang, K.
Deposit date:2008-11-09
Release date:2009-11-17
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
4EQ1
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CRYSTAL STRUCTURE OF THE ARNT PAS-B HOMODIMER
Descriptor:Aryl hydrocarbon receptor nuclear translocator, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL
Authors:Gardner, K.H., Key, J.M.
Deposit date:2012-04-17
Release date:2013-04-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules.
Acs Chem.Biol., 8, 2013
4RYO
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CRYSTAL STRUCTURE OF BCTSPO TYPE II HIGH RESOLUTION MONOMER
Descriptor:Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate, DIMETHYL SULFOXIDE
Authors:Guo, Y., Liu, Q., Hendrickson, W.A., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2014-12-15
Release date:2015-04-22
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
5WUC
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STRUCTURAL BASIS FOR CONDUCTANCE THROUGH TRIC CATION CHANNELS
Descriptor:Uncharacterized protein, SODIUM ION
Authors:Su, M., Gao, F., Mao, Y., Li, D.L., Guo, Y.Z., Wang, X.H., Bruni, R., Kloss, B., Hendrickson, W.A., Chen, Y.H., New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-07-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
6A4X
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OXIDASE CHAP-H2
Descriptor:Bleomycin resistance protein, FE (II) ION
Authors:Zhang, B., Wang, Y.S., Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
6BDE
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CRYSTAL STRUCTURE OF FE(II) UNLIGANDED H-NOX PROTEIN MUTANT A71G FROM K. ALGICIDA
Descriptor:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bruegger, J.J., Hespen, C.W., Marletta, M.A.
Deposit date:2017-10-22
Release date:2018-05-30
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Native Alanine Substitution in the Glycine Hinge Modulates Conformational Flexibility of Heme Nitric Oxide/Oxygen (H-NOX) Sensing Proteins.
ACS Chem. Biol., 13, 2018
3G6M
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CRYSTAL STRUCTURE OF A CHITINASE CRCHI1 FROM THE NEMATOPHAGOUS FUNGUS CLONOSTACHYS ROSEA IN COMPLEX WITH A POTENT INHIBITOR CAFFEINE
Descriptor:Chitinase, CAFFEINE
Authors:Gan, Z., Yang, J., Lou, Z., Rao, Z., Zhang, K.-Q.
Deposit date:2009-02-06
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure and mutagenesis analysis of chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with the inhibitor caffeine
Microbiology, 156, 2010