7L97

Crystal structure of STAMBPL1 in complex with an engineered binder

Summary for 7L97

• Entry DOI: 10.2210/pdb7l97/pdb
• Descriptor: AMSH-like protease, Ubiquitin variant, ZINC ION, ... (7 entities in total)
• Functional Keywords: stambp1, ubv, structural genomics, structural genomics consortium, sgc, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 28877.83

Authors

Guo, Y.,Dong, A.,Hou, F.,Li, Y.,Zhang, W.,Arrowsmith, C.H.,Edwards, A.M.,Tong, Y.,Structural Genomics Consortium (SGC) (deposition date: 2021-01-02, release date: 2021-08-25, Last modification date: 2023-10-18)

• Primary citation: Guo, Y.,Liu, Q.,Mallette, E.,Caba, C.,Hou, F.,Fux, J.,LaPlante, G.,Dong, A.,Zhang, Q.,Zheng, H.,Tong, Y.,Zhang, W.; Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.; J.Biol.Chem., 297:101107-101107, 2021; PubMed: 34425109; DOI: 10.1016/j.jbc.2021.101107

Experimental method

X-RAY DIFFRACTION (2.01 Å)