Author results

1C8J
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CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F)
Descriptor:CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Liu, Y., Jiang, F., Guo, Q., Chen, X., Jin, J., Sun, Y., Rao, Z.
Deposit date:2000-05-31
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F)
To be Published
1GH2
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF A NEW HUMAN THIOREDOXIN-LIKE PROTEIN
Descriptor:THIOREDOXIN-LIKE PROTEIN
Authors:Jin, J., Chen, X., Guo, Q., Yuan, J., Qiang, B., Rao, Z.
Deposit date:2000-11-01
Release date:2001-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of the catalytic domain of a human thioredoxin-like protein.
Eur.J.Biochem., 269, 2002
1GIS
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A TRICHOSANTHIN(TCS) MUTANT(E85Q) COMPLEX STRUCTURE WITH 2'-DEOXY-ADENOSIN-5'-MONOPHOSPHATE
Descriptor:RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE
Authors:Guo, Q., Liu, Y., Dong, Y., Rao, Z.
Deposit date:2001-03-15
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16, 2003
1GIU
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A TRICHOSANTHIN(TCS) MUTANT(E85R) COMPLEX STRUCTURE WITH ADENINE
Descriptor:RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, ADENINE
Authors:Guo, Q., Liu, Y., Dong, Y., Rao, Z.
Deposit date:2001-03-15
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.
Protein Eng., 16, 2003
1J51
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CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F/V247L/C334A) WITH 1,3,5-TRICHLOROBENZENE
Descriptor:CYTOCHROME P450CAM, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Chen, X., Christopher, A., Jones, J., Guo, Q., Xu, F., Cao, R., Wong, L.L., Rao, Z.
Deposit date:2002-01-05
Release date:2002-01-23
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the F87W/Y96F/V247L mutant of cytochrome P-450cam with 1,3,5-trichlorobenzene bound and further protein engineering for the oxidation of pentachlorobenzene and hexachlorobenzene
J.BIOL.CHEM., 277, 2002
1S26
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STRUCTURE OF ANTHRAX EDEMA FACTOR-CALMODULIN-ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE COMPLEX REVEALS AN ALTERNATIVE MODE OF ATP BINDING TO THE CATALYTIC SITE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Bohm, A., Tang, W.-J.
Deposit date:2004-01-08
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004
1SK6
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN, 3',5' CYCLIC AMP (CAMP), AND PYROPHOSPHATE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
Authors:Guo, Q., Shen, Y., Zhukovskaya, N.L., Tang, W.J.
Deposit date:2004-03-04
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
J.Biol.Chem., 279, 2004
1XFU
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) TRUNCATION MUTANT, EF-DELTA 64 IN COMPLEX WITH CALMODULIN
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFV
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 3' DEOXY-ATP
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Q., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFW
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 3'5' CYCLIC AMP (CAMP)
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFX
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN IN THE PRESENCE OF 10 MILLIMOLAR EXOGENOUSLY ADDED CALCIUM CHLORIDE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFY
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFZ
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN IN THE PRESENCE OF 1 MILLIMOLAR EXOGENOUSLY ADDED CALCIUM CHLORIDE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.J.
Deposit date:2004-09-15
Release date:2005-05-03
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XUO
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X-RAY STRUCTURE OF LFA-1 I-DOMAIN BOUND TO A 1,4-DIAZEPANE-2,5-DIONE INHIBITOR AT 1.8A RESOLUTION
Descriptor:Integrin alpha-L, MAGNESIUM ION, (2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHYL)-1,4-DIAZEPAN-1-YL]-N-METHYL-3-(2-NAPHTHYL)PROPANAMIDE
Authors:Wattanasin, S., Kallen, J., Myers, S., Guo, Q., Sabio, M., Ehrhardt, C., Albert, R., Hommel, U., Weckbecker, G., Welzenbach, K.
Deposit date:2004-10-26
Release date:2005-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1
Bioorg.Med.Chem.Lett., 15, 2005
1Y0V
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CRYSTAL STRUCTURE OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND PYROPHOSPHATE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, MAGNESIUM ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Guo, Q., Florian, J., Tang, W.-J.
Deposit date:2004-11-16
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor
Embo J., 24, 2005
1YRT
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CRYSTAL STRUCTURE ANALYSIS OF THE ADENYLYL CYCLAES CATALYTIC DOMAIN OF ADENYLYL CYCLASE TOXIN OF BORDETELLA PERTUSSIS IN PRESENCE OF C-TERMINAL CALMODULIN
Descriptor:Bifunctional hemolysin-adenylate cyclase, Calmodulin, CALCIUM ION
Authors:Guo, Q., Shen, Y., Lee, Y.S., Gibbs, C.S., Mrksich, M., Tang, W.J.
Deposit date:2005-02-04
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
1YRU
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CRYSTAL STRUCTURE ANALYSIS OF THE ADENYLYL CYCLAES CATALYTIC DOMAIN OF ADENYLYL CYCLASE TOXIN OF BORDETELLA PERTUSSIS IN PRESENCE OF C-TERMINAL CALMODULIN AND 1MM CALCIUM CHLORIDE
Descriptor:Bifunctional hemolysin-adenylate cyclase, Calmodulin, CALCIUM ION
Authors:Guo, Q., Shen, Y., Tang, W.J.
Deposit date:2005-02-04
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin
Embo J., 24, 2005
1ZOT
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CRYSTAL STRUCTURE ANALYSIS OF THE CYAA/C-CAM WITH PMEAPP
Descriptor:CyaA with C-terminal Calmodulin, Calmodulin, MAGNESIUM ION, ...
Authors:Guo, Q., Tang, W.J.
Deposit date:2005-05-13
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
2COL
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CRYSTAL STRUCTURE ANALYSIS OF CYAA/C-CAM WITH PYROPHOSPHATE
Descriptor:Bifunctional hemolysin-adenylate cyclase, Calmodulin, MAGNESIUM ION, ...
Authors:Guo, Q., Tang, W.J., Shen, Y.
Deposit date:2005-05-18
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin
Embo J., 24, 2005
2FXD
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X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE IRM MUTANT COMPLEXED WITH ATAZANAVIR (BMS-232632)
Descriptor:pol protein, SULFATE ION, ACETATE ION, ...
Authors:Klei, H.E., Sheriff, S.
Deposit date:2006-02-04
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
J.Virol., 81, 2007
2FXE
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X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE CRM MUTANT COMPLEXED WITH ATAZANAVIR (BMS-232632)
Descriptor:pol protein, SULFATE ION, ACETATE ION, ...
Authors:Sheriff, S., Klei, H.E.
Deposit date:2006-02-05
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
J.Virol., 81, 2007
2PQ3
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N-TERMINAL CALMODULIN ZN-TRAPPED INTERMEDIATE
Descriptor:Calmodulin, CACODYLATE ION, ZINC ION
Authors:Warren, J.T., Guo, Q., Tang, W.J.
Deposit date:2007-05-01
Release date:2007-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step.
J.Mol.Biol., 374, 2007
2WBY
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH INSULIN
Descriptor:INSULIN-DEGRADING ENZYME, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Manolopoulou, M., Guo, Q., Malito, E., Schilling, A.B., Tang, W.J.
Deposit date:2009-03-06
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
2WC0
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CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN
Descriptor:INSULIN-DEGRADING ENZYME, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Manolopoulou, M., Guo, Q., Malito, E., Schilling, A.B., Tang, W.J.
Deposit date:2009-03-06
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
2WK3
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH AMYLOID-BETA (1-42)
Descriptor:INSULIN DEGRADING ENZYME, BETA-AMYLOID PROTEIN 42, ZINC ION
Authors:Guo, Q., Tang, W.J.
Deposit date:2009-06-05
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Molecular Basis for the Recognition and Cleavages of Igf-II, Tgf-Alpha, and Amylin by Human Insulin Degrading Enzyme.
J.Mol.Biol., 395, 2010