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6FC2
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BU of 6fc2 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
Descriptor: CALCIUM ION, Eukaryotic translation initiation factor 4E, Protein EAP1
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FBZ
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BU of 6fbz by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC3
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BU of 6fc3 by Molmil
Crystal structure of the eIF4E-p20 complex from Saccharomyces cerevisiae
Descriptor: Cap-associated protein CAF20, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC1
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BU of 6fc1 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC0
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BU of 6fc0 by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum
Descriptor: Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.293 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
5T47
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BU of 5t47 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex
Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T46
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BU of 5t46 by Molmil
Crystal structure of the human eIF4E-eIF4G complex
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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BU of 5t48 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
4MZS
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BU of 4mzs by Molmil
Mouse cathepsin s with covalent ligand (3S,4S)-1-[(2-CHLOROPHENYL)SULFONYL]-N-[(2E)-2-IMINOETHYL]-4-(MORPHOLIN-4-YLCARBONYL)PYRROLIDINE-3-CARBOXAMIDE
Descriptor: (3S,4S)-1-[(2-chlorophenyl)sulfonyl]-N-[(2E)-2-iminoethyl]-4-(morpholin-4-ylcarbonyl)pyrrolidine-3-carboxamide, Cathepsin S
Authors:Kuglstatter, A, Stihle, M.
Deposit date:2013-09-30
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.
J.Med.Chem., 56, 2013
4MZO
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BU of 4mzo by Molmil
Mouse cathepsin s with covalent ligand (3S,4S)-N-[(2E)-2-IMINOETHYL]-4-(MORPHOLIN-4-YLCARBONYL)-1-(PHENYLSULFONYL)PYRROLIDINE-3-CARBOXAMIDE
Descriptor: (3S,4S)-N-[(2E)-2-iminoethyl]-4-(morpholin-4-ylcarbonyl)-1-(phenylsulfonyl)pyrrolidine-3-carboxamide, Cathepsin S
Authors:Kuglstatter, A, Stihle, M.
Deposit date:2013-09-30
Release date:2014-09-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.
J.Med.Chem., 56, 2013
4BSQ
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BU of 4bsq by Molmil
MOUSE CATHEPSIN S WITH COVALENT LIGAND
Descriptor: (1R,2R,4R)-N-(2-azanylideneethyl)-2-morpholin-4-ylcarbonyl-4-(phenylsulfonyl)cyclopentane-1-carboxamide, CATHEPSIN S, SULFATE ION
Authors:Banner, D.W, Benz, J, Gsell, B, Stihle, M, Ruf, A, Hilpert, H.
Deposit date:2013-06-11
Release date:2013-11-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Identification of Potent and Selective Cathepsin S (Cats) Inhibitors Containing Different Central Cyclic Scaffolds.
J.Med.Chem., 56, 2013
4BS5
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BU of 4bs5 by Molmil
MOUSE CATHEPSIN S WITH COVALENT LIGAND
Descriptor: (2S,4R)-N-[1-(iminomethyl)cyclopropyl]-4-[2-(trifluoromethyl)phenyl]sulfonyl-pyrrolidine-2-carboxamide, CATHEPSIN S
Authors:Banner, D.W, Benz, J, Gsell, B, Stihle, M, Ruf, A, Haap, W.
Deposit date:2013-06-07
Release date:2013-11-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Identification of Potent and Selective Cathepsin S (Cats) Inhibitors Containing Different Central Cyclic Scaffolds.
J.Med.Chem., 56, 2013

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PDB entries from 2024-09-18

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