4BSQ
MOUSE CATHEPSIN S WITH COVALENT LIGAND
Summary for 4BSQ
Entry DOI | 10.2210/pdb4bsq/pdb |
Related | 4BPV 4BQV 4BS5 4BS6 |
Descriptor | CATHEPSIN S, (1R,2R,4R)-N-(2-azanylideneethyl)-2-morpholin-4-ylcarbonyl-4-(phenylsulfonyl)cyclopentane-1-carboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase, cysteine protease |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Lysosome: O70370 |
Total number of polymer chains | 1 |
Total formula weight | 25454.22 |
Authors | Banner, D.W.,Benz, J.,Gsell, B.,Stihle, M.,Ruf, A.,Hilpert, H. (deposition date: 2013-06-11, release date: 2013-11-27, Last modification date: 2024-05-01) |
Primary citation | Hilpert, H.,Mauser, H.,Humm, R.,Anselm, L.,Kuehne, H.,Hartmann, G.,Gruener, S.,Banner, D.W.,Benz, J.,Gsell, B.,Kuglstatter, A.,Stihle, M.,Thoma, R.,Alvarez-Sanchez, R.,Iding, H.,Wirz, B.,Haap, W. Identification of Potent and Selective Cathepsin S (Cats) Inhibitors Containing Different Central Cyclic Scaffolds. J.Med.Chem., 56:9789-, 2013 Cited by PubMed: 24224654DOI: 10.1021/JM401528K PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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