4BSQ

MOUSE CATHEPSIN S WITH COVALENT LIGAND

Summary for 4BSQ

Entry DOI	10.2210/pdb4bsq/pdb
Related	4BPV 4BQV 4BS5 4BS6
Descriptor	CATHEPSIN S, (1R,2R,4R)-N-(2-azanylideneethyl)-2-morpholin-4-ylcarbonyl-4-(phenylsulfonyl)cyclopentane-1-carboxamide, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, cysteine protease
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Lysosome: O70370
Total number of polymer chains	1
Total formula weight	25454.22
Authors	Banner, D.W.,Benz, J.,Gsell, B.,Stihle, M.,Ruf, A.,Hilpert, H. (deposition date: 2013-06-11, release date: 2013-11-27, Last modification date: 2024-05-01)
Primary citation	Hilpert, H.,Mauser, H.,Humm, R.,Anselm, L.,Kuehne, H.,Hartmann, G.,Gruener, S.,Banner, D.W.,Benz, J.,Gsell, B.,Kuglstatter, A.,Stihle, M.,Thoma, R.,Alvarez-Sanchez, R.,Iding, H.,Wirz, B.,Haap, W. Identification of Potent and Selective Cathepsin S (Cats) Inhibitors Containing Different Central Cyclic Scaffolds. J.Med.Chem., 56:9789-, 2013 Cited by PubMed: 24224654 DOI: 10.1021/JM401528K PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation