Author results

1Y6W
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TRAPPED INTERMEDIATE OF CALMODULIN
Descriptor:Calmodulin, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Grabarek, Z.
Deposit date:2004-12-07
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a Trapped Intermediate of Calmodulin: Calcium Regulation of EF-hand Proteins from a New Perspective.
J.Mol.Biol., 346, 2005
1LVC
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 2' DEOXY, 3' ANTHRANILOYL ATP
Descriptor:calmodulin-sensitive adenylate cyclase, calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Lee, Y.-S., Soelaiman, S., Bergson, P., Lu, D., Chen, A., Beckingham, K., Grabarek, Z., Mrksich, M., Tang, W.-J.
Deposit date:2002-05-28
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins
Embo J., 21, 2002
5ID3
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SOLUTION STRUCTURE OF THE PORE-FORMING REGION OF C. ELEGANS MITOCHONDRIAL CALCIUM UNIPORTER (MCU)
Descriptor:Mitochondrial Calcium Uniporter
Authors:Oxenoid, K., Dong, Y., Cao, C., Cui, T., Sancak, Y., Markhard, A.L., Grabarek, Z., Kong, L., Liu, Z., Ouyang, B., Cong, Y., Mootha, V.K., Chou, J.J., Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2016-02-23
Release date:2016-05-04
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Architecture of the mitochondrial calcium uniporter.
Nature, 533, 2016
1K8T
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF)
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, SULFATE ION, NICKEL (II) ION
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-25
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin
Nature, 415, 2002
1K90
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 3' DEOXY-ATP
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, YTTERBIUM (III) ION, ...
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-26
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
1K93
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, SULFATE ION, ...
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-26
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
3UCT
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STRUCTURE OF MN2+-BOUND N-TERMINAL DOMAIN OF CALMODULIN IN THE PRESENCE OF ZN2+
Descriptor:Calmodulin, MANGANESE (II) ION, ZINC ION
Authors:Senguen, F.T., Grabarek, Z.
Deposit date:2011-10-27
Release date:2012-08-08
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
3UCW
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STRUCTURE OF MG2+ BOUND N-TERMINAL DOMAIN OF CALMODULIN
Descriptor:Calmodulin, MAGNESIUM ION
Authors:Senguen, F.T., Grabarek, Z.
Deposit date:2011-10-27
Release date:2012-08-08
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
3UCY
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STRUCTURE OF MG2+ BOUND N-TERMINAL DOMAIN OF CALMODULIN IN THE PRESENCE OF ZN2+
Descriptor:Calmodulin, SODIUM ION, MAGNESIUM ION, ...
Authors:Senguen, F.T., Grabarek, Z.
Deposit date:2011-10-27
Release date:2012-08-08
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
5ER0
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WATER-FORMING NADH OXIDASE FROM LACTOBACILLUS BREVIS (LBNOX)
Descriptor:NADH oxidase, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ...
Authors:Cracan, V., Grabarek, Z.
Deposit date:2015-11-13
Release date:2016-04-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.
Science, 352, 2016
5VN0
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WATER-FORMING NADH OXIDASE FROM LACTOBACILLUS BREVIS (LBNOX) BOUND TO NADH.
Descriptor:NAD(FAD)-dependent dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ...
Authors:Cracan, V., Grabarek, Z.
Deposit date:2017-04-28
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells.
Nat. Chem. Biol., 13, 2017
5VOH
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CRYSTAL STRUCTURE OF ENGINEERED WATER-FORMING NADPH OXIDASE (TPNOX) BOUND TO NADPH. THE G159A, D177A, A178R, M179S, P184R MUTANT OF LBNOX.
Descriptor:NADH oxidase, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Cracan, V., Grabarek, Z.
Deposit date:2017-05-02
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells.
Nat. Chem. Biol., 13, 2017
6EAZ
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APO STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN MICU2
Descriptor:Calcium uptake protein 2, mitochondrial, GLYCEROL
Authors:Kamer, K.J., Grabarek, Z.
Deposit date:2018-08-03
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1N2D
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TERNARY COMPLEX OF MLC1P BOUND TO IQ2 AND IQ3 OF MYO2P, A CLASS V MYOSIN
Descriptor:Myosin Light Chain, IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN
Authors:Terrak, M., Wu, G., Stafford, W.F., Lu, R.C., Dominguez, R.
Deposit date:2002-10-22
Release date:2003-11-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
1TN4
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FOUR CALCIUM TNC
Descriptor:TROPONIN C, CALCIUM ION
Authors:Love, M.L., Dominguez, R., Houdusse, A., Cohen, C.
Deposit date:1997-09-18
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
2A3Z
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TERNARY COMPLEX OF THE WH2 DOMAIN OF WASP WITH ACTIN-DNASE I
Descriptor:Actin, alpha skeletal muscle, Deoxyribonuclease-1, ...
Authors:Chereau, D., Kerff, F., Dominguez, R.
Deposit date:2005-06-27
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.078 Å)
Cite:Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A40
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TERNARY COMPLEX OF THE WH2 DOMAIN OF WAVE WITH ACTIN-DNASE I
Descriptor:Actin, alpha skeletal muscle, Deoxyribonuclease-1, ...
Authors:Chereau, D., Kerff, F., Dominguez, R.
Deposit date:2005-06-27
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A41
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TERNARY COMPLEX OF THE WH2 DOMAIN OF WIP WITH ACTIN-DNASE I
Descriptor:Actin, alpha skeletal muscle, Deoxyribonuclease-1, ...
Authors:Chereau, D., Kerff, F., Dominguez, R.
Deposit date:2005-06-27
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A42
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ACTIN-DNASE I COMPLEX
Descriptor:Actin, alpha skeletal muscle, Deoxyribonuclease-1, ...
Authors:Chereau, D., Kerff, F., Dominguez, R.
Deposit date:2005-06-27
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
2TN4
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FOUR CALCIUM TNC
Descriptor:TROPONIN C, CALCIUM ION
Authors:Love, M.L., Dominguez, R., Houdusse, A., Cohen, C.
Deposit date:1997-09-18
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
5VXC
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN CLYBL IN COMPLEX WITH FREE COASH
Descriptor:Citrate lyase subunit beta-like protein, mitochondrial, COENZYME A, ...
Authors:Shen, H.
Deposit date:2017-05-23
Release date:2017-11-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.872 Å)
Cite:The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
5VXO
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN CLYBL IN COMPLEX WITH PROPIONYL-COA
Descriptor:Citrate lyase subunit beta-like protein, mitochondrial, propionyl Coenzyme A, ...
Authors:Shen, H.
Deposit date:2017-05-23
Release date:2017-11-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.266 Å)
Cite:The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
5VXS
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN CLYBL IN APO FORM
Descriptor:Citrate lyase subunit beta-like protein, mitochondrial, CITRIC ACID
Authors:Shen, H.
Deposit date:2017-05-24
Release date:2017-11-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.954 Å)
Cite:The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
1PK0
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CRYSTAL STRUCTURE OF THE EF3-CAM COMPLEXED WITH PMEAPP
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Tang, W.J.
Deposit date:2003-06-04
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.
Proc.Natl.Acad.Sci.USA, 101, 2004
1S26
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STRUCTURE OF ANTHRAX EDEMA FACTOR-CALMODULIN-ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE COMPLEX REVEALS AN ALTERNATIVE MODE OF ATP BINDING TO THE CATALYTIC SITE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Bohm, A., Tang, W.-J.
Deposit date:2004-01-08
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004