1K8T

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF)

Summary for 1K8T

DescriptorCALMODULIN-SENSITIVE ADENYLATE CYCLASE, SULFATE ION, NICKEL (II) ION, ... (4 entities in total)
Functional Keywordsedema factor, adenylyl cyclase, anthrax, calmodulin, toxin, lyase
Biological sourceBacillus anthracis
Cellular locationSecreted P40136
Total number of polymer chains1
Total molecular weight59253.55
Authors
Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. (deposition date: 2001-10-25, release date: 2002-01-23, Last modification date: 2011-07-13)
Primary citation
Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J.
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin
Nature, 415:396-402, 2002
PubMed: 11807546 (PDB entries with the same primary citation)
DOI: 10.1038/415396a
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.275220.8%8.5%12.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload